Citation: Xue Wenting, Di Zhenghan, Zhao Ya, Zhang Aiping, Li Lele. DNA-mediated coordinative assembly of upconversion hetero-nanostructures for targeted dual-modality imaging of cancer cells[J]. Chinese Chemical Letters, ;2019, 30(4): 899-902. doi: 10.1016/j.cclet.2019.03.022 shu

DNA-mediated coordinative assembly of upconversion hetero-nanostructures for targeted dual-modality imaging of cancer cells

Xue Wenting ^a,b ,
Di Zhenghan ^b,c ,
Zhao Ya ^b ,
Zhang Aiping ^a,**, ,
Li Lele ^b,c,*,

a.
College of Pharmacy, Shanxi Medical University, Taiyuan 030001, China
b.
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China
c.
University of Chinese Academy of Sciences, Beijing 100049, China

_**

zhangap1@163.com

lilele@nanoctr.cn

Received Date: 28 February 2019
Revised Date: 7 March 2019
Accepted Date: 11 March 2019
Available Online: 15 April 2019

Figures(4)

superstructures has enormous potential in material sciences and engineering. Despite the potential, controlled assembly of different kinds of NPs into spatially addressable hybrid configurations still remains a formidable challenge. Herein, we report a simple and universal strategy for DNA-mediated assembly of CdTe quantum dots (QDs) and lanthanide-doped upconversion nanoparticles (UCNPs). Such DNA-QD/UCNPs heterostructures not only maintains both fluorescent properties of QDs and upconversion luminescence behaviors of UCNPs, but also offers a polyvalent DNA surface, allowing for targeted dual-modality imaging of cancer cells using an aptamer. The hetero-assembly mediated by the DNA inorganic interfacial interaction may provide a scalable way to fabricate hybrid superstructures of both theoretical and practical interests.
- Bioimaging,
- Upconversion nanoparticles,
- Self-assembly,
- Quantum dots,
- Cancer targeting
1. [1]
  L. Wang, L. Xu, H. Kuang, et al., Acc. Chem. Res. 45(2012) 1916-1926. doi: 10.1021/ar200305f
2. [2]
  Z. Nie, A. Petukhova, E. Kumacheva, Nat. Nanotechnol. 5(2010) 15-25. doi: 10.1038/nnano.2009.453
3. [3]
  S. Srivastava, N.A. Kotov, Acc. Chem. Res. 41(2008) 1831-1841. doi: 10.1021/ar8001377
4. [4]
  Y. He, T. Ye, A.E. Ribbe, et al., J. Am. Chem. Soc. 133(2011) 1742-1744. doi: 10.1021/ja1060092
5. [5]
  L. Xu, H. Kuang, C. Xu, et al., J. Am. Chem. Soc. 134(2012) 1699-1709. doi: 10.1021/ja2088713
6. [6]
  Y. Xia, T. Nguyen, M. Yang, et al., Nat. Nanotechnol. 7(2012) 479. doi: 10.1038/nnano.2012.106
7. [7]
  L.H. Tan, H. Xing, Y. Lu, Acc. Chem. Res. 47(2014) 1881-1890. doi: 10.1021/ar500081k
8. [8]
  C.A. Mirkin, R.L. Letsinger, R.C. Mucic, et al., Nature 382(1996) 607-609. doi: 10.1038/382607a0
9. [9]
  M.R. Jones, N.C. Seeman, C.A. Mirkin, Science 347(2015) 1260901. doi: 10.1126/science.1260901
10. [10]
  L.Y.T. Chou, K. Zagorovsky, W.C.W. Chan, Nat. Nanotechnol. 9(2014) 148-155. doi: 10.1038/nnano.2013.309
11. [11]
  R. Schreiber, J. Do, E.M. Roller, et al., Nat. Nanotechnol. 9(2014) 74-78. doi: 10.1038/nnano.2013.253
12. [12]
  Y. Zhang, F. Lu, K.G. Yager, et al., Nat. Nanotechnol. 8(2013) 865-872. doi: 10.1038/nnano.2013.209
13. [13]
  R. Wang, C. Nuckolls, S.J. Wind, Angew. Chem. Int. Ed. 51(2012) 11325-11327. doi: 10.1002/anie.201206389
14. [14]
  L.L. Li, Y. Lu, J. Am. Chem. Soc. 137(2015) 5272-5275. doi: 10.1021/jacs.5b01092
15. [15]
  B. Liu, Z. Huang, J. Liu, Angew. Chem. Int. Ed. 57(2018) 9439-9442. doi: 10.1002/anie.201805532
16. [16]
  W. Zhou, R. Saran, J. Liu, Chem. Rev. 117(2017) 8272-8325. doi: 10.1021/acs.chemrev.7b00063
17. [17]
  L.L. Li, P. Wu, K. Hwang, et al., J. Am. Chem. Soc. 135(2013) 2411-2414. doi: 10.1021/ja310432u
18. [18]
  M. Li, C. Wang, Z. Di, et al., Angew. Chem. Int. Ed. 58(2019) 1350-1354. doi: 10.1002/anie.201810735
19. [19]
  F. Wang, Y. Han, C.S. Lim, et al., Nature 463(2010) 1061-1065. doi: 10.1038/nature08777
20. [20]
  M. Haase, H. Schäfer, Angew. Chem. Int. Ed. 50(2011) 5808-5829. doi: 10.1002/anie.v50.26
21. [21]
  H. Dong, S.R. Du, X.Y. Zheng, et al., Chem. Rev. 115(2015) 10725-10815. doi: 10.1021/acs.chemrev.5b00091
22. [22]
  N.M. Idris, M.K. Gnanasammandhan, J. Zhang, et al., Nat. Med.18(2012) 1580-1585. doi: 10.1038/nm.2933
23. [23]
  W. Ma, P. Fu, M. Sun, et al., J. Am. Chem. Soc. 139(2017) 11752-11759. doi: 10.1021/jacs.7b03617
24. [24]
  J. Zhou, Q. Liu, W. Feng, et al., Chem. Rev. 115(2015) 395-465. doi: 10.1021/cr400478f
25. [25]
  J. Zhao, J. Gao, W. Xue, et al., J. Am. Chem. Soc. 140(2018) 578-581. doi: 10.1021/jacs.7b11161
26. [26]
  B. Zhou, B. Shi, D. Jin, et al., Nat. Nanotechnol. 10(2015) 924-936. doi: 10.1038/nnano.2015.251
27. [27]
  R. Shi, X. Ling, X. Li, et al., Nanoscale 9(2017) 13739-13746. doi: 10.1039/C7NR04877G
28. [28]
  Y. Wang, G. Yang, Y. Wang, et al., Nanoscale 9(2017) 4759-4769. doi: 10.1039/C6NR09030C
29. [29]
  Z. Li, H. Liu, H. Li, et al., Sens. Actuators B Chem. 280(2019) 94-101. doi: 10.1016/j.snb.2018.10.057
30. [30]
  G. Tian, X. Zhang, Z. Gu, et al., Adv. Mater. 27(2015) 7692-7712. doi: 10.1002/adma.201503280
31. [31]
  Y. Zhang, L. Zhang, R. Deng, et al., J. Am. Chem. Soc. 136(2014) 4893-4896. doi: 10.1021/ja5013646
32. [32]
  Y. Li, Z. Di, J. Gao, et al., J. Am. Chem. Soc. 139(2017) 13804-13810. doi: 10.1021/jacs.7b07302
33. [33]
  K. Ding, L. Jing, C. Liu, et al., Biomaterials 35(2014) 1608-1617. doi: 10.1016/j.biomaterials.2013.10.078
34. [34]
  G. Tikhomirov, S. Hoogland, P.E. Lee, et al., Nat. Nanotechnol. 6(2011) 485-490. doi: 10.1038/nnano.2011.100
35. [35]
  C. Yan, A. Dadvand, F. Rosei, et al., J. Am. Chem. Soc. 132(2010) 8868-8869. doi: 10.1021/ja103743t
36. [36]
  N. Ma, E.H. Sargent, S.O. Kelley, Nat. Nanotechnol. 4(2009) 121-125. doi: 10.1038/nnano.2008.373
37. [37]
  J.H. Lee, M.V. Yigit, D. Mazumdar, et al., Adv. Drug Deliv. Rev. 62(2010) 592-605. doi: 10.1016/j.addr.2010.03.003
38. [38]
  S. Soundararajan, W. Chen, E.K. Spicer, et al., Cancer Res. 68(2008) 2358-2365. doi: 10.1158/0008-5472.CAN-07-5723
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