Citation: Zhou Chao, Diao Pinhui, Li Xiaoji, Ge Yanqin, Guo Cheng. Facile photochemical synthesis of α-ketoamides and quinoxalines from amines and benzoylacetonitrile under mild conditions[J]. Chinese Chemical Letters, ;2019, 30(2): 371-374. doi: 10.1016/j.cclet.2018.06.019 shu

Facile photochemical synthesis of α-ketoamides and quinoxalines from amines and benzoylacetonitrile under mild conditions

College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China

guocheng@njtech.edu.cn

Received Date: 29 April 2018
Revised Date: 28 May 2018
Accepted Date: 11 June 2018
Available Online: 12 February 2018

Figures(5)

A selective protocol for the synthesis of either α-ketoamides or quinoxaline derivatives under the same reaction conditions has been achieved simply by varying substitution number of amino-groups. The method features metal-free, room temperature and broad substrate scopes as well as no extra oxidant. This process applies to various substituent groups and gives products in moderate to good yield. Finally, a rational mechanism was proposed.
- Visible light,
- Metal-free,
- Catalyst-free,
- Addititives-free,
- Room-temperature
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