Citation: Zhang Di, Feng Feng, Liu Ruping, Zhu Wenjia, Yao Li. Mechanochemistry in cancer cell metastasis[J]. Chinese Chemical Letters, ;2019, 30(1): 7-14. doi: 10.1016/j.cclet.2018.06.011 shu

Mechanochemistry in cancer cell metastasis

Zhang Di ^a,b ,
Feng Feng ^a,b ,
Liu Ruping ^c ,
Zhu Wenjia ^c ,
Yao Li ^a,b,,

a.
State Key Laboratory for Structural Chemistry of Unstable and Stable Species, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Science, Beijing 100190, China
b.
University of Chinese Academy of Sciences, Beijing 100049, China
c.
Beijing Institute of Graphic Communication, Beijing 102600, China

Corresponding author: Yao Li, yaoli@iccas.ac.cn
Received Date: 25 April 2018
Revised Date: 4 June 2018
Accepted Date: 6 June 2018
Available Online: 7 January 2018

Figures(5)

Metastasis is the leading cause of death in people with cancer. In the series of steps comprising metastasis process, mechanochemistry plays crucial roles. In this review, we introduced the mechanical factors in cancer cell metastasis, intracellular mechanical sensors and methods for measuring the mechanical forces of tumor cells. The recent researches on the contribution of mechanochemistry to metastasis and future perspectives were summarized.
- Mechanochemistry,
- Mechanical force,
- Adhesion,
- Migration,
- Tumor metastasis
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