Citation: Wang Lianhui, Xiong Dan, Jie Lianghua, Yu Chudan, Cui Xiuling. Rhodium-catalyzed oxidative homologation of N-pyrimidyl indolines with alkynes via dual C—H activation: Facile synthesis of benzo[g] indolines[J]. Chinese Chemical Letters, ;2018, 29(6): 907-910. doi: 10.1016/j.cclet.2018.05.007 shu

Rhodium-catalyzed oxidative homologation of N-pyrimidyl indolines with alkynes via dual C—H activation: Facile synthesis of benzo[g] indolines

Engineering Research Center of Molecular Medicine, Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, China

Corresponding author: Cui Xiuling, cuixl@hqu.edu.cn
Received Date: 28 April 2018
Revised Date: 2 May 2018
Accepted Date: 3 May 2018
Available Online: 5 June 2018

Figures(5)

We herein report a highly regioselective rhodium-catalyzed C6-and C7—H bond functionalization of indolines with alkynes by using 2-pyrimidine as a directing group. Moreover, NH-free benzo[g]indole unit could be obtained by an oxidation/removal of the directing group sequence.
- Rhodium,
- Indoline,
- Alkyne,
- Benzo[g]indoline,
- C—H activation
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