Citation: Zhao Xinmei, Zeng Leyong, Hosmane Narayan, Gong Yan, Wu Aiguo. Cancer cell detection and imaging: MRI-SERS bimodal splat-shaped Fe₃O₄/Au nanocomposites[J]. Chinese Chemical Letters, ;2019, 30(1): 87-89. doi: 10.1016/j.cclet.2018.01.028 shu

Cancer cell detection and imaging: MRI-SERS bimodal splat-shaped Fe₃O₄/Au nanocomposites

a.
CAS Key Laboratory of Magnetic Materials and Devices & Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China
b.
Zhejiang Pharmaceutical College, Ningbo 315100, China
c.
Department of Chemistry & Biochemistry, Northern Illinois University, DeKalb, Illinois 60115-2862, United States
d.
Ningbo Eye Hospital, Ningbo 315040, China

Corresponding author: Wu Aiguo, aiguo@nimte.ac.cn
Received Date: 14 September 2017
Revised Date: 10 January 2018
Accepted Date: 15 January 2018
Available Online: 31 January 2018

Figures(4)

The development of multifunctional contrast agents contributes significant character in the diagnosis of cancer. However, still efforts are required to design and improve the biocompatibility of contrast agents for early detection of cancer. Herein, we synthesized splat shape Fe₃O₄/Au nanocomposites for multimode biomedical applications. Transmission electron microscopy (TEM) results showed that the splat-like Fe₃O₄/Au structure was in the range of 130 nm and homogeneously distributed in the aqueous medium. The nanocomposites were incubated with MCF-7 cells to investigate the magnetic resonance imaging (MRI) and surface-enhanced Raman scattering (SERS) activities. The excellent T₂ MRI and enhanced SERS properties were obtained without any cytotoxicity. These results demonstrated that assynthesized splat-shaped Fe₃O₄/Au nanocomposites may be a promising MRI/SERS dual probe for the tumor detection.
- Fe₃O₄/Au,
- MRI,
- SERS,
- Cell detection,
- MCF-7
1. [1]
  N. Lee, H. Cho, M. Oh, et al., J. Am. Chem. Soc. 134(2012) 10309-10312. doi: 10.1021/ja3016582
2. [2]
  X. Zhu, J. Zhou, M. Chen, et al., Biomaterials 33(2012) 4618-4627. doi: 10.1016/j.biomaterials.2012.03.007
3. [3]
  J. Liu, Z. Li, X. Yang, et al., Chem. Commun. 51(2015) 13369-13372. doi: 10.1039/C5CC04911C
4. [4]
  G. Hu, N. Li, J. Tang, S. Xu, L. Wang, ACS Appl. Mater. Interfaces 8(2016) 22830-22838. doi: 10.1021/acsami.6b05510
5. [5]
  W. Song, Z. Mao, X. Liu, et al., Nanoscale 4(2012) 2333-2338. doi: 10.1039/c2nr12030e
6. [6]
  T. Vo-Dinh, Y. Liu, A.M. Fales, et al., Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 7(2015) 17-33. doi: 10.1002/wnan.1283
7. [7]
  M. Yigit, L. Zhu, M. Ifediba, et al., ACS Nano 5(2011) 1056-1066. doi: 10.1021/nn102587h
8. [8]
  M. Kircher, A. Zerda, J. Jokerst, et al., Nat. Med. 18(2012) 829-835. doi: 10.1038/nm.2721
9. [9]
  Y. Zhang, L. Wang, E. Tan, S. Yang, L. Guo, Chin. Chem. Lett. 26(2015) 1426-1430. doi: 10.1016/j.cclet.2015.06.004
10. [10]
  Z. Duan, X. Gao, T. Li, Kai Yao, X. Xie, Chin. Chem. Lett. 28(2017) 521-524.
11. [11]
  Z. Gan, A. Zhao, M. Zhang, et al., J. Nanopart. Res. 15(2013) 1954. doi: 10.1007/s11051-013-1954-1
12. [12]
  L. Lou, K. Yu, Z. Zhang, et al., Nano Res. 5(2012) 272-282. doi: 10.1007/s12274-012-0207-4
13. [13]
  C. Li, T. Chen, I. Ocsoy, et al., Adv. Funct. Mater. 24(2014) 1772-1780. doi: 10.1002/adfm.v24.12
14. [14]
  X. Zhou, W. Xu, Y. Wang, et al., J. Phys. Chem. C 114(2010) 19607-19613. doi: 10.1021/jp106949v
15. [15]
  V. Amendola, S. Scaramuzza, L. Litti, et al., Small 10(2014) 2476-2486. doi: 10.1002/smll.v10.12
16. [16]
  J. Liu, Z. Sun, Y. Deng, et al., Angew. Chem. Int. Ed. 48(2009) 5875-5879. doi: 10.1002/anie.v48:32
17. [17]
  L. Lou, K. Yu, Z. Zhang, et al., Appl. Surf. Sci. 258(2012) 8521-8526. doi: 10.1016/j.apsusc.2012.05.031
18. [18]
  C. Xu, J. Xie, D. Ho, et al., Angew. Chem. Int. Ed. 47(2008) 173-176. doi: 10.1002/(ISSN)1521-3773
19. [19]
  S. Narayanan, B.N. Sathy, U. Mony, et al., ACS Appl. Mater. Interfaces 4(2012) 251-260. doi: 10.1021/am201311c
20. [20]
  X. Ma, A. Gong, L. Xiang, et al., J. Mater. Chem. B 1(2013) 3419-3428. doi: 10.1039/c3tb20648c
21. [21]
  Z. Liang, X. Wu, Y. Xie, S. Liu, Chin. J. Chem. 30(2012) 1387-1392. doi: 10.1002/cjoc.v30.7
22. [22]
  T. Zhou, B. Wu, D. Xing, J. Mater. Chem. 22(2012) 470-477. doi: 10.1039/C1JM13692E
23. [23]
  Y. Zhai, J. Zhai, Y. Wang, et al., J. Phys. Chem. C 113(2009) 7009-7014. doi: 10.1021/jp810561q
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2. [2]
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Cancer cell detection and imaging: MRI-SERS bimodal splat-shaped Fe3O4/Au nanocomposites

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通讯作者: 陈斌, bchen63@163.com

Cancer cell detection and imaging: MRI-SERS bimodal splat-shaped Fe₃O₄/Au nanocomposites