Citation: Ning Peng, Wang Wenjuan, Chen Man, Feng Yan, Meng Xiangming. Recent advances in mitochondria-and lysosomes-targeted small-molecule two-photon fluorescent probes[J]. Chinese Chemical Letters, ;2017, 28(10): 1943-1951. doi: 10.1016/j.cclet.2017.09.026 shu

Recent advances in mitochondria-and lysosomes-targeted small-molecule two-photon fluorescent probes

School of Chemistry and Chemical Engineering & Center for Atomic Engineering of Advanced Materials & Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei 230601, China

Corresponding author: Feng Yan, fy70@163.com Meng Xiangming, mengxm@ahu.edu.cn
Received Date: 25 July 2017
Revised Date: 5 September 2017
Accepted Date: 7 September 2017
Available Online: 10 October 2017

Figures(8)

Mitochondria and lysosomes are essential cellular organelles in most eukaryotic cells by playing the physiological roles to support the normal functions of cells, as well as the life of the whole body. To date, small-molecule fluorescent probes have been considered as one of the vital tools for monitoring and visualizing multiple biological analytes. This review summarized the recent advances in small-molecule two-photon fluorescent probes for metal ions, reactive oxygen species (ROS) and reactive sulfur species (RSS), and changes inside micro-environment (e.g., pH, viscosity and polarity) in mitochondria and lysosomes, or served as mitotracker and lysotracker with the assistance of two-photon microscopy.
- Two-photon absorption,
- Fluorescent probe,
- Localization,
- Mitochondria,
- Lysosomes
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沈阳化工大学材料科学与工程学院沈阳 110142