Citation: Lei Zuhai, Zeng Zhenhua, Qian Xuhong, Yang Youjun. A novel chromogenic and fluorogenic scaffold for detection of oxidative radicals[J]. Chinese Chemical Letters, ;2017, 28(10): 2001-2004. doi: 10.1016/j.cclet.2017.09.023 shu

A novel chromogenic and fluorogenic scaffold for detection of oxidative radicals

Lei Zuhai ^b ,
Zeng Zhenhua ^b ,
Qian Xuhong ^a,b ,
Yang Youjun ^a,b,,

a.
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China
b.
Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

Corresponding author: Yang Youjun, youjunyang@ecust.edu.cn
Received Date: 7 July 2017
Revised Date: 6 September 2017
Accepted Date: 7 September 2017
Available Online: 8 October 2017

Figures(5)

Radical detection has attracted significant attention recently. Here we have developed a scaffold through covalent assembly principle (OR570), which could facile applications in detection of oxidative radicals. The primary advantage of the assembly type probe lies at the turn-on fluorescence signal from a zero background and hence high fluorescence turn-on ratio for sensitive detection of weak signal.
- Radicals,
- Fluorescent probe,
- Covalent assembly,
- Nitrogen dioxide,
- Fluorogenic
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