Citation: Luo Ai-Min, Shao Yongliang, Zhang Ke-Jia, Wang Ya-Wen, Peng Yu. Syntheses of three terbium complexes as fluorescent probes and their application on the pH detection of routine urine test[J]. Chinese Chemical Letters, ;2017, 28(10): 2009-2013. doi: 10.1016/j.cclet.2017.08.037 shu

Syntheses of three terbium complexes as fluorescent probes and their application on the pH detection of routine urine test

State Key Laboratory of Applied Organic Chemistry and College of Chemical Engineering, Lanzhou University, Lanzhou 730000, China

Corresponding author: Wang Ya-Wen, ywwang@lzu.edu.cn Peng Yu, pengyu@lzu.edu.cn
Received Date: 29 June 2017
Revised Date: 8 August 2017
Accepted Date: 15 August 2017
Available Online: 31 October 2017

Figures(7)

By modifying the salicylic-acid moiety with electron-withdrawing or -donating groups, three new terbium complexes (L^Ⅰ·Tb, L^Ⅱ·Tb, L^Ⅲ·Tb) based on tripodal carboxylate ligands were synthesized. Due to different pull-push electronic effects of ligands, the fluorescence intensities of these terbium complexes significantly varied, that is:L^Ⅱ·Tb > L^Ⅲ·Tb > L^Ⅰ·Tb. Meanwhile, the characteristic peaks at 492 nm (⁵D₄ → ⁷F₆) and 547 nm (⁵D₄ → ⁷F₅) showed "Off-On-Off" fluorescence response to various pH conditions, which indicated that all of them can be used as the highly sensitive pH fluorescent probes. Notably, using L^Ⅱ Tb with the best fluorescence performance as a probe, some patients' urine samples can be easily monitored through the response triggered by pH value. Therefore, L^Ⅱ Tb has the potential to auxiliarily diagnose some diseases in clinical practice through pH detection of routine urine test.
- Fluorescent probe,
- Terbium complex,
- pH Detection,
- Ligand,
- Routine urine test
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