Citation: Chen Yuanyuan, Zhang Tingting, Gao Xiaonan, Pan Wei, Li Na, Tang Bo. A highly selective and instantaneous upconversion fluorescent nanoprobe for ascorbic acid detection in biological samples[J]. Chinese Chemical Letters, ;2017, 28(10): 1983-1986. doi: 10.1016/j.cclet.2017.08.024 shu

A highly selective and instantaneous upconversion fluorescent nanoprobe for ascorbic acid detection in biological samples

College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Molecular and Nano Science, Shandong Normal University, Ji'nan 250014, China

Corresponding author: Li Na, lina@sdnu.edu.cn
Received Date: 7 June 2017
Revised Date: 12 July 2017
Accepted Date: 14 August 2017
Available Online: 19 October 2017

Figures(4)

Ascorbic acid (AA) serves as a key coenzyme in many metabolic pathways. Enough daily AA supplements from different dietary sources are the only way for human to maintain their AA levels in body. Determination of AA content in different foods guides to build healthy diet, which is of great biomedical significance. Hence, developing a highly selective and instantaneous fluorescent nanoprobe for the detection of AA in biological samples is highly needed. Here we present a novel turn-on fluorescent nanoprobe using lanthanide-doped upconversion nanoparticles (UCNPs) and cobalt oxyhydroxide (CoOOH) nanoflakes for monitoring AA in fruit samples. In this nanosystem, the UCNPs can be adsorbed onto the CoOOH nanoflakes, leading to a remarkable fluorescence decrease through Förster resonance energy transfer. Furthermore, the AA could trigger the disassembly of the CoOOH to liberate the upconverted fluorescence. The UCNPs-based nanoprobe can provide an effective platform for highly selective and rapid detection of AA in biological samples.
- Cobalt oxyhydroxide nanoflakes,
- Upconversion nanoparticles,
- Ascorbic acid,
- Fluorescent nanoprobe,
- Biological samples
1. [1]
  E.R. Stadtman, B.S. Berlett, Chem. Res. Toxicol. 10(1997) 485-494. doi: 10.1021/tx960133r
2. [2]
  Q. Chen, M.G. Espey, A.Y. Sun, et al., Proc. Natl. Acad. Sci. 105(2008) 11105-11109. doi: 10.1073/pnas.0804226105
3. [3]
  G. Gegelashvili, A. Schousboe, Brain Res. Bull. 45(1998) 233-238. doi: 10.1016/S0361-9230(97)00417-6
4. [4]
  M.E. Rice, Trends Neurosci. 23(2000) 209-216. doi: 10.1016/S0166-2236(99)01543-X
5. [5]
  A. Bossi, S.A. Piletsky, E.V. Piletska, P.G. Righetti, A.P.F. Turner, Anal. Chem. 72(2000) 4296-4300. doi: 10.1021/ac000185s
6. [6]
  J. Fu, X.H. Tan, Y.H. Li, X.J. Song, Chin. Chem. Lett. 27(2016) 1541-1546. doi: 10.1016/j.cclet.2016.07.007
7. [7]
  X.M. Fu, Z.J. Liu, S.X. Cai, et al., Chin. Chem. Lett. 27(2016) 920-926. doi: 10.1016/j.cclet.2016.04.014
8. [8]
  N. Li, C.Y. Chang, W. Pan, B. Tang, Angew. Chem. Int. Ed. 51(2012) 7426-7430. doi: 10.1002/anie.201203767
9. [9]
  L.M. Yang, N. Li, W. Pan, Z.Z. Yu, B. Tang, Anal. Chem. 87(2015) 3678-3684. doi: 10.1021/ac503975x
10. [10]
  M.M. Luan, N. Li, W. Pan, et al., Chem. Commun. 53(2017) 356-359. doi: 10.1039/C6CC07605J
11. [11]
  W. Pan, T.T. Zhang, H.J. Yang, et al., Anal. Chem. 85(2013) 10581-10588. doi: 10.1021/ac402700s
12. [12]
  N. Li, W. Diao, Y.Y. Han, et al., Chem. Eur. J. 20(2014) 16488-16491. doi: 10.1002/chem.201404625
13. [13]
  Y.L. Xu, X.Y. Niu, H.L. Chen, S.G. Zhao, X.G. Chen, Chin. Chem. Lett. 28(2017) 338-344. doi: 10.1016/j.cclet.2016.10.003
14. [14]
  G.F. Wang, A.X. Guan, C.Y. Zhou, et al., Chin. Chem. Lett. 27(2016) 1788-1792. doi: 10.1016/j.cclet.2016.07.012
15. [15]
  Y. Li, Y.M. Miao, M.Q. Yang, Y.X. Wu, G.Q. Yan, Chin. Chem. Lett. 27(2016) 773-778. doi: 10.1016/j.cclet.2016.01.006
16. [16]
  L.L. Xi, H.B. Ma, G.H. Tao, Chin. Chem. Lett. 27(2016) 1531-1536. doi: 10.1016/j.cclet.2016.03.002
17. [17]
  R. Yu, C.F. Jiang, W. Chu, M.F. Ran, W.J. Sun, Chin. Chem. Lett. 28(2017) 302-306. doi: 10.1016/j.cclet.2016.07.014
18. [18]
  Y.J. Chen, X.P. Yan, Small 5(2009) 2012-2018. doi: 10.1002/smll.v5:17
19. [19]
  L.B. Li, C. Wang, K.Y. Liu, et al., Anal. Chem. 87(2015) 3404-3411. doi: 10.1021/ac5046609
20. [20]
  H.M. Meng, X.B. Zhang, C. Yang, et al., Anal. Chem. 88(2016) 6057-6063. doi: 10.1021/acs.analchem.6b01352
21. [21]
  N. Li, Y.H. Li, Y.Y. Han, et al., Anal. Chem. 86(2014) 3924-3930. doi: 10.1021/ac5000587
22. [22]
  Z.Z. Yu, W. Pan, N. Li, B. Tang, Chem. Sci. 7(2016) 4237-4244. doi: 10.1039/C6SC00737F
23. [23]
  Z.Z. Yu, Q.Q. Sun, W. Pan, N. Li, B. Tang, ACS Nano 9(2015) 11064-11704. doi: 10.1021/acsnano.5b04501
24. [24]
  J.L. Liu, Y. Liu, Q. Liu, et al., J. Am. Chem. Soc. 133(2011) 15276-15279. doi: 10.1021/ja205907y
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