Citation: Pan Gaifang, Jin Xin, Mou Quanbing, Zhang Chuan. Recent progress on DNA block copolymer[J]. Chinese Chemical Letters, ;2017, 28(9): 1822-1828. doi: 10.1016/j.cclet.2017.08.022 shu

Recent progress on DNA block copolymer

School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China

Author Bio:

Quanbing Mou completed his BSc degree in Polymer Materials and Engineering from Sichuan University in 2012. Then he strated to pursue his PhD degree under the supervision of Prof. Deyue Yan, Prof. Xinyuan Zhu, and Prof. Chuan Zhang in the School of Chemistry and Chemical Engineering at Shanghai Jiao Tong University. Currently, he is working on the design and synthesis of functional nucleic acid materials, as well as their application in biomedical fields
Chuan Zhang got his bachelor and master degree of Chemistryat Tsinghua University. After that, he continued his PhD study at Purdue University and obtained the PhD degree in Chemistry in 2011 under supervision of Prof. Chengde Mao. Then he received the postdoctoral training in the group of Prof. Chad A. Mirkin at Northwestern University, USA. He joined the School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University as a tenure-track Associate Professor in 2014. His main research interests focus on DNA supramolecular chemistry, DNA-based nanomaterials for biomedical applications, and cell-material interactions
Corresponding author: Mou Quanbing, quanbingmou@sjtu.edu.cn Zhang Chuan, chuanzhang@sjtu.edu.cn

Received Date: 27 June 2017
Revised Date: 23 July 2017
Accepted Date: 14 August 2017
Available Online: 18 September 2017

Figures(13)

DNA has gained great attention because of its unique structure, excellent molecular recognition property, and biological functions. When married with versatile synthetic polymers, the DNA conjugated polymer hybrids, known as DNA block copolymers (DBCs), have been launched and well developed for the syntheses of new materials and nanostructures with different functions in the past several decades. Compared to conventional synthetic block copolymers, using DNA as a building block provides several advantages over other polymer candidates, such as molecular recognition, programmable self-assembly, biocompatibility, and sequence-encoded information. In this review, recent developments in this area will be summarized and meaningful breakthroughs will be highlighted. We will discuss representative examples of recent progress in the syntheses, structure manipulations, and applications of DBCs.
- DNA block copolymer,
- Self-assembly,
- Nanostructure,
- Hybrid material,
- Micelle
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