Citation: D. Sheybani Natasha, Yang Hu. Pediatric ocular nanomedicines:Challenges and opportunities[J]. Chinese Chemical Letters, ;2017, 28(9): 1817-1821. doi: 10.1016/j.cclet.2017.07.022 shu

Pediatric ocular nanomedicines:Challenges and opportunities

D. Sheybani Natasha ^a ,
Yang Hu ^b,c,d,,

a.
Department of Biomedical Engineering, Virginia Commonwealth University, Richmond VA 23284, United States
b.
Department of Chemical & Life Science Engineering, Virginia Commonwealth University, Richmond VA 23219, United States
c.
Department of Pharmaceutics, Virginia Commonwealth University, Richmond VA 23298, United States
d.
Massey Cancer Center, Virginia Commonwealth University, Richmond VA 23298, United States

Corresponding author: Yang Hu, hyang2@vcu.edu
Received Date: 27 April 2017
Revised Date: 20 July 2017
Accepted Date: 21 July 2017
Available Online: 26 September 2017

Figures(4)

The eye is a highly complex, yet readily accessible organ within the human body. As such, the eye is an appealing candidate target for a vast array of drug therapies. Despite advances in ocular drug therapy research, the focus on pediatric ocular drug delivery continues to be highly underrepresented due to the limited number of degenerative ocular diseases with childhood onset. In this review, we explore more deeply the reasons underlying the disparity between ocular therapies available for children and for adults by highlighting diseases that most commonly afflict children (with focus on the anterior eye) and existing prognoses, recent developments in ocular drug delivery systems and nanomedicines for children, and barriers to use for pediatric patients
- Pediatric,
- Ocular drug delivery,
- Nanomedicine,
- Drug administration,
- Compliance
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