Citation: Wan Guangping, Xia Hongjun, Wang Jun, Liu Jiawei, Song Botao, Yang Ying, Bai Quan. Synthesis of SiO₂@SiO₂ core-shell microspheres using urea-formaldehyde polymers as the templates for fast separation of small solutes and proteins[J]. Chinese Chemical Letters, ;2018, 29(1): 213-216. doi: 10.1016/j.cclet.2017.06.004 shu

Synthesis of SiO₂@SiO₂ core-shell microspheres using urea-formaldehyde polymers as the templates for fast separation of small solutes and proteins

Wan Guangping ^a ,
Xia Hongjun ^a ,
Wang Jun ^a,b ,
Liu Jiawei ^a ,
Song Botao ^a ,
Yang Ying ^a ,
Bai Quan ^a,,

a.
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Modern Separation Science, Key Lab of Modern Separation Science in Shaanxi Province, Northwest University, Xi'an 710069, China
b.
Shaanxi Research Design Institute of Petroleum and Chemical Industry, Shaanxi Dangerous Chemical Supervision and Inspection Center, Xi'an 710054, China

Corresponding author: Bai Quan, baiquan@nwu.edu.cn
Received Date: 23 March 2017
Revised Date: 26 April 2017
Accepted Date: 2 June 2017
Available Online: 4 January 2017

Figures(6)

Superficially porous core-shell silica microspheres (CSSMs) have been a great success for the fast separation of small molecules and proteins in recent years. In this paper, the CSSMs were synthesized by an improved polymerization-induced colloid aggregation (PICA) method using urea-formaldehyde polymers as the templates. The agglomeration of the functionalized silica core was avoided by the surface modification through reflux with ureidopropyltrimethoxysilane in the neutral ethanol solution at 80℃, and the secondary nucleation of the silica nanoparticles during the preparation process could also be inhibited via the optimization of the reaction conditions, such as pH, temperature, colloidal silica sol concentration and the reaction time. The controllable shell thickness and pore size of the synthesized monodisperse CSSMs were successfully obtained by adjusting the weight ratio of silica core/colloidal silica sol and the particle size of colloidal silica sol, respectively. The C18-modified CSSMs with different pore sizes were used to separate small solutes and proteins. The higher efficient separation and relatively low back pressure of the synthesized core-shell column demonstrate that the CSSMs have a great potential application for fast HPLC.
- Core-shell silica microsphere,
- Polymerization-induced colloid aggregation,
- Urea-formaldehyde polymers,
- Fast separation,
- HPLC
1. [1]
  Y.X. Wang, K.L. Zhao, F. Yang, et al., Chin. Chem. Lett. 26(2015) 988-992. doi: 10.1016/j.cclet.2015.05.001
2. [2]
  Y.J. Ma, C. Guan, Y.J. Dong, et al., Chin. Chem. Lett. 27(2016) 749-752. doi: 10.1016/j.cclet.2016.01.023
3. [3]
  C. Guan, H. Yu, Chin. Chem. Lett. 26(2015) 1371-1375. doi: 10.1016/j.cclet.2015.08.004
4. [4]
  I. Ali, V.D. Gaitonde, A. Grahn, J. Chromatogr. Sci. 48(2010) 386-394. doi: 10.1093/chromsci/48.5.386
5. [5]
  V. González-Ruiz, A.I. Olives, M.A. Martín, Trends in Anal. Chem. 64(2015) 17-28. doi: 10.1016/j.trac.2014.08.008
6. [6]
  F. Gritti, G. Guiochon, J. Chromatogr. A 1228(2012) 2-19. doi: 10.1016/j.chroma.2011.07.014
7. [7]
  I. Ali, Z.A. AL-Othman, M. Al-Za'abi, Biomed. Chromatogr. 26(2012) 1001-1008.
8. [8]
  C.G. Horvath, B.A. Preiss, S.R. Lipsky, Anal. Chem. 39(1967) 1422-1428. doi: 10.1021/ac60256a003
9. [9]
  J.J. Kirkland, Anal. Chem. 64(1992) 1239-1245. doi: 10.1021/ac00035a009
10. [10]
  J.J. Kirkland, F.A. Truszkowski, C.H. Dilks Jr., et al., J. Chromatogr. A 890(2000) 3-13. doi: 10.1016/S0021-9673(00)00392-7
11. [11]
  L.E. Blue, J.W. Jorgenson, J. Chromatogr. A 1218(2011) 7989-7995. doi: 10.1016/j.chroma.2011.09.004
12. [12]
  H. Dong, J.D. Brennan, Chem. Commun. 47(2011) 1207-1209. doi: 10.1039/C0CC04221H
13. [13]
  R.A. Caruso, M. Antonietti, Chem. Mater. 13(2001) 3272-3282. doi: 10.1021/cm001257z
14. [14]
  S.A. Schuster, B.M. Wagner, B.E. Boyes, et al., J. Chromatogr. Sci. 48(2010) 566-571. doi: 10.1093/chromsci/48.7.566
15. [15]
  B.M. Wagner, S.A. Schuster, B.E. Boyes, et al., J. Chromatogr. A 1264(2012) 22-30. doi: 10.1016/j.chroma.2012.09.052
16. [16]
  W. Chen, T. C. Wei, Patent: US7846337B2.
17. [17]
  W. Chen, K. Jiang, A. Mack, et al., J. Chromatogr. A 1414(2015) 147-157. doi: 10.1016/j.chroma.2015.08.043
18. [18]
  W. Stöber, A. Fink, E. Bohn, J. Colloid. Interface. Sci. 26(1968) 62-69. doi: 10.1016/0021-9797(68)90272-5
1. [1]
  Min Song , Qian Zhang , Tao Shen , Guanyu Luo , Deli Wang . Surface reconstruction enabled o-PdTe@Pd core-shell electrocatalyst for efficient oxygen reduction reaction. Chinese Chemical Letters, 2024, 35(8): 109083-. doi: 10.1016/j.cclet.2023.109083
2. [2]
  Shudi Yu , Jie Li , Jiongting Yin , Wanyu Liang , Yangping Zhang , Tianpeng Liu , Mengyun Hu , Yong Wang , Zhengying Wu , Yuefan Zhang , Yukou Du . Built-in electric field and core-shell structure of the reconstructed sulfide heterojunction accelerated water splitting. Chinese Chemical Letters, 2024, 35(12): 110068-. doi: 10.1016/j.cclet.2024.110068
3. [3]
  Bing Niu , Honggao Huang , Liwei Luo , Li Zhang , Jianbo Tan . Coating colloidal particles with a well-defined polymer layer by surface-initiated photoinduced polymerization-induced self-assembly and the subsequent seeded polymerization. Chinese Chemical Letters, 2025, 36(2): 110431-. doi: 10.1016/j.cclet.2024.110431
4. [4]
  Shaonan Tian , Yu Zhang , Qing Zeng , Junyu Zhong , Hui Liu , Lin Xu , Jun Yang . Core-shell gold-copper nanoparticles: Evolution of copper shells on gold cores at different gold/copper precursor ratios. Chinese Journal of Structural Chemistry, 2023, 42(11): 100160-100160. doi: 10.1016/j.cjsc.2023.100160
5. [5]
  Hengying Xiang , Nanping Deng , Lu Gao , Wen Yu , Bowen Cheng , Weimin Kang . 3D core-shell nanofibers framework and functional ceramic nanoparticles synergistically reinforced composite polymer electrolytes for high-performance all-solid-state lithium metal battery. Chinese Chemical Letters, 2024, 35(8): 109182-. doi: 10.1016/j.cclet.2023.109182
6. [6]
  Yuan Zhang , Shenghao Gong , A.R. Mahammed Shaheer , Rong Cao , Tianfu Liu . Plasmon-enhanced photocatalytic oxidative coupling of amines in the air using a delicate Ag nanowire@NH₂-UiO-66 core-shell nanostructures. Chinese Chemical Letters, 2024, 35(4): 108587-. doi: 10.1016/j.cclet.2023.108587
7. [7]
  Zhefei Hu , Jingwen Liao , Jiawen Zhou , Lulu Zhao , Yanjuan Liu , Yuefei Zhang , Wei Chen , Sheng Tang . A new green approach to synthesizing MIP-202@porous silica microspheres for positional isomer/enantiomer/hydrophilic separation. Chinese Chemical Letters, 2025, 36(1): 109985-. doi: 10.1016/j.cclet.2024.109985
8. [8]
  Guo-Hong Gao , Run-Ze Zhao , Ya-Jun Wang , Xiao Ma , Yan Li , Jian Zhang , Ji-Sen Li . Core–shell heterostructure engineering of CoP nanowires coupled NiFe LDH nanosheets for highly efficient water/seawater oxidation. Chinese Chemical Letters, 2024, 35(8): 109181-. doi: 10.1016/j.cclet.2023.109181
9. [9]
  Peng Meng , Qian-Cheng Luo , Aidan Brock , Xiaodong Wang , Mahboobeh Shahbazi , Aaron Micallef , John McMurtrie , Dongchen Qi , Yan-Zhen Zheng , Jingsan Xu . Molar ratio induced crystal transformation from coordination complex to coordination polymers. Chinese Chemical Letters, 2024, 35(4): 108542-. doi: 10.1016/j.cclet.2023.108542
10. [10]
  Shuo Li , Qianfa Liu , Lijun Mao , Xin Zhang , Chunju Li , Da Ma . Benzothiadiazole-based water-soluble macrocycle: Synthesis, aggregation-induced emission and selective detection of spermine. Chinese Chemical Letters, 2024, 35(11): 109791-. doi: 10.1016/j.cclet.2024.109791
11. [11]
  Haixia Wu , Kailu Guo . Iodized polyacrylonitrile as fast-charging anode for lithium-ion battery. Chinese Chemical Letters, 2024, 35(10): 109550-. doi: 10.1016/j.cclet.2024.109550
12. [12]
  Lingling Su , Qunyan Wu , Congzhi Wang , Jianhui Lan , Weiqun Shi . Theoretical design of polyazole based ligands for the separation of Am(Ⅲ)/Eu(Ⅲ). Chinese Chemical Letters, 2024, 35(8): 109402-. doi: 10.1016/j.cclet.2023.109402
13. [13]
  Jingwen Zhao , Jianpu Tang , Zhen Cui , Limin Liu , Dayong Yang , Chi Yao . A DNA micro-complex containing polyaptamer for exosome separation and wound healing. Chinese Chemical Letters, 2024, 35(9): 109303-. doi: 10.1016/j.cclet.2023.109303
14. [14]
  Huangjie Lu , Yingzhe Du , Peng Lin , Jian Lin . Separation of americium from lanthanides based on oxidation state control. Chinese Journal of Structural Chemistry, 2024, 43(10): 100344-100344. doi: 10.1016/j.cjsc.2024.100344
15. [15]
  Hao-Cong Li , Ming Zhang , Qiyan Lv , Kai Sun , Xiao-Lan Chen , Lingbo Qu , Bing Yu . Homogeneous catalysis and heterogeneous separation: Ionic liquids as recyclable photocatalysts for hydroacylation of olefins. Chinese Chemical Letters, 2025, 36(2): 110579-. doi: 10.1016/j.cclet.2024.110579
16. [16]
  Jun-Jie Fang , Zheng Liu , Yun-Peng Xie , Xing Lu . Superatomic Ag₅₈ nanoclusters incorporating a [MS₄@Ag₁₂]²⁺ (M = Mo or W) kernel show aggregation-induced emission. Chinese Chemical Letters, 2024, 35(10): 109345-. doi: 10.1016/j.cclet.2023.109345
17. [17]
  Xuejian Xing , Pan Zhu , E Pang , Shaojing Zhao , Yu Tang , Zheyu Hu , Quchang Ouyang , Minhuan Lan . D-A-D-structured boron-dipyrromethene with aggregation-induced enhanced phototherapeutic efficiency for near-infrared fluorescent and photoacoustic imaging-guided synergistic photodynamic and photothermal cancer therapy. Chinese Chemical Letters, 2024, 35(10): 109452-. doi: 10.1016/j.cclet.2023.109452
18. [18]
  Longlong Geng , Huiling Liu , Wenfeng Zhou , Yong-Zheng Zhang , Hongliang Huang , Da-Shuai Zhang , Hui Hu , Chao Lv , Xiuling Zhang , Suijun Liu . Construction of metal-organic frameworks with unsaturated Cu sites for efficient and fast reduction of nitroaromatics: A combined experimental and theoretical study. Chinese Chemical Letters, 2024, 35(8): 109120-. doi: 10.1016/j.cclet.2023.109120
19. [19]
  Xiao Zhu , Yanbing Mo , Jiawei Chen , Gaopan Liu , Yonggang Wang , Xiaoli Dong . A weakly-solvated ether-based electrolyte for fast-charging graphite anode. Chinese Chemical Letters, 2024, 35(8): 109146-. doi: 10.1016/j.cclet.2023.109146
20. [20]
  Yang Deng , Yitao Ouyang , Chao Han . Constriction-susceptible makes fast cycling of lithium metal in solid-state batteries: Silicon as an example. Chinese Journal of Structural Chemistry, 2024, 43(7): 100276-100276. doi: 10.1016/j.cjsc.2024.100276

Get Citation

PDF

XML

Metrics

PDF Downloads(7)
Abstract views(657)
HTML views(39)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Synthesis of SiO2@SiO2 core-shell microspheres using urea-formaldehyde polymers as the templates for fast separation of small solutes and proteins

Metrics

通讯作者: 陈斌, bchen63@163.com

Synthesis of SiO₂@SiO₂ core-shell microspheres using urea-formaldehyde polymers as the templates for fast separation of small solutes and proteins