Citation: Ling-Jie Meng, Qing-Lan Guo, Cheng-Gen Zhu, Cheng-Bo Xu, Jian-Gong Shi. Isatindigodiphindoside, an alkaloid glycoside with a new diphenylpropylindole skeleton from the root of Isatis indigotica[J]. Chinese Chemical Letters, ;2018, 29(1): 119-122. doi: 10.1016/j.cclet.2017.05.019 shu

Isatindigodiphindoside, an alkaloid glycoside with a new diphenylpropylindole skeleton from the root of Isatis indigotica

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

Corresponding author: Jian-Gong Shi, shijg@imm.ac.cn
Received Date: 1 April 2017
Revised Date: 2 May 2017
Accepted Date: 17 May 2017
Available Online: 20 January 2017

Figures(6)

A novel indole alkaloid glycoside with an unprecedented 2-(diphenylpropyl)indole skeleton, isatindigodiphindoside (1), was isolated from an aqueous extract of the roots of Isatis indigotica. The structure was determined by extensive spectroscopic studies, especially by 2D NMR data analysis combined with enzymatic hydrolysis and ECD calculations. Plausible biosynthetic pathways of compound 1 are also discussed.
- Cruciferae,
- Isatis indigotica,
- Ban lan gen,
- Diphenylpropylindole,
- Alkaloid glycoside,
- Isatindigodiphindoside
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