Citation: Lei-Lei Rui, Hong-Liang Cao, Yu-Dong Xue, Li-Chao Liu, Lei Xu, Yun Gao, Wei-An Zhang. Functional organic nanoparticles for photodynamic therapy[J]. Chinese Chemical Letters, ;2016, 27(8): 1412-1420. doi: 10.1016/j.cclet.2016.07.011 shu

Functional organic nanoparticles for photodynamic therapy

Shanghai Key Laboratory of Advanced Polymeric Materials, East China University of Science and Technology, Shanghai 200237, China

Corresponding author: Hong-Liang Cao, caohl@ecust.edu.cn Yun Gao, zhqpan@ecust.edu.cn Wei-An Zhang, wazhang@ecust.edu.cn
Received Date: 3 May 2016
Revised Date: 5 July 2016
Accepted Date: 6 July 2016
Available Online: 18 August 2016

Figures(7)

In recent years, cancer has been one of the leading causes of death in the world. Much effort has been devoted to developing cancer treatments. Photodynamic therapy (PDT) is a noninvasive therapeutic modality by combining the light of a specific wavelength, a photosensitizer (PS) and oxygen, which has been widely applied for the treatment of cancers. However, the application of PDT in clinic is greatly limited due to lack of tumor selectivity and often causing skin photosensitivity. The use of organic nanoparticles (NPs) as an advanced technology in the field of PDT shows a great promise to overcome these shortcomings. Therefore, in this review, we summarize several functional organic NPs as PS carriers that have been developed to enhance the efficacy of PDT against cancers.
- Photosensitizers,
- Photodynamic therapy,
- Organic nanoparticles,
- Singlet oxygen,
- Cancer treatment
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沈阳化工大学材料科学与工程学院沈阳 110142