Citation: Zhi-Wei Chen, Jun-Bo Hou, Zhao-Ran Dai, Xiao-Feng Yang. A regioselective synthesis of pentacyclic compounds containing coumarin, pyrrole, indene without catalysts under microwave irradiation[J]. Chinese Chemical Letters, ;2016, 27(10): 1622-1625. doi: 10.1016/j.cclet.2016.04.009 shu

A regioselective synthesis of pentacyclic compounds containing coumarin, pyrrole, indene without catalysts under microwave irradiation

Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China

Corresponding author: Zhi-Wei Chen, chenzhiwei@zjut.edu.cn
Received Date: 2 March 2016
Revised Date: 25 March 2016
Accepted Date: 6 April 2016
Available Online: 22 October 2016

Figures(2)

A concise and efficient approach was developed for the synthesis of pentacyclic compounds containing coumarin, pyrrole, indene in a regioselective manner in good yields via the reactions of N-substituted 4-aminocoumarin compounds and ninhydrin using microwave irradiation. No catalysts are required in our protocol.
- 4-Aminocoumarin,
- Catalyst-free,
- Ninhydrin,
- Regioselective,
- Annulation
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