Citation: Hanan A. Soliman, Ahmed Y. Mubarak, Saad S. Elmorsy. An efficient synthesis of bis(indolyl) methanes and N,N'-alkylidene bisamides by Silzic under solvent free conditions[J]. Chinese Chemical Letters, ;2016, 27(03): 353-356. doi: 10.1016/j.cclet.2015.11.013 shu

An efficient synthesis of bis(indolyl) methanes and N,N'-alkylidene bisamides by Silzic under solvent free conditions

a.
a. Photochemistry Department, National Research Centre, Dokki, Cairo 12622, Egypt;
b.
b. Chemistry Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt

Corresponding author: Hanan A. Soliman,
Received Date: 17 August 2015
Available Online: 12 November 2015

An operationally simple and green method for the synthesis of a wide range of bis(indolyl)methanes, and N,N'-alkylidene bisamides undermild conditions, with excellent yields using Silzic, has been developed. This improved method furnishes in good yields bis(indolyl)methanes derivatives starting from indole and aldehydes, or ketones, and N,N'-alkylidene bisamides derivatives starting from acetamide and aldehydes. The catalytic system was reused up to three times with the same efficiency.
- Bis(indolyl)methanes,
- N,N'-alkylidenebisamides,
- Acetamide,
- Mild conditions,
- Silzic
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