Citation: Hui-Qiao Wang, Zhao-Xiang Deng. Gel electrophoresis as a nanoseparation tool serving DNA nanotechnology[J]. Chinese Chemical Letters, ;2015, 26(12): 1435-1438. doi: 10.1016/j.cclet.2015.10.019 shu

Gel electrophoresis as a nanoseparation tool serving DNA nanotechnology

Hui-Qiao Wang ^a,b ,
Zhao-Xiang Deng ^b,,

1.
a College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China;
2.
b Department of Chemistry, University of Science and Technology of China, Hefei 230026, China

Corresponding author: Zhao-Xiang Deng,
Received Date: 31 August 2015
Available Online: 27 October 2015

The past years have witnessed a rapid development of DNA nanotechnology in nanomaterials science with a central focus on programmable material construction on the nanoscale. An efficient method is therefore highly desirable (but challenging) for analytical/preparative purification of DNA-conjugated nano-objects and their DNA-assemblies. In this regard, agarose gel electrophoresis, a traditional technique that has been invented for biomacromolecule separation, has found many innovative uses. This includes shape, size, charge, and ligand-valence separations of nanoparticle building blocks as well as monitoring a self-assembly process towards product identification and purification.
- Gel electrophoresis
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