Citation: Ying Long, Jia Zhou, Mei-Pan Yang, Bing-Qin Yang. A selective and sensitive off-on probe for palladium and its application for living cell imaging[J]. Chinese Chemical Letters, ;2016, 27(02): 205-210. doi: 10.1016/j.cclet.2015.09.003 shu

A selective and sensitive off-on probe for palladium and its application for living cell imaging

1.
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an 710069, China

Corresponding author: Bing-Qin Yang,
Received Date: 31 March 2015
Available Online: 10 June 2015
Fund Project: This work was supported by the National Natural Science Foundation of China (No. 21172178). (No. 21172178)

A new rhodamine B derivative T1 has been rationally synthesized and displayed selective Pd(Ⅱ)-amplified absorbance and fluorescence emission above 540 nm in methanol-water. Upon the addition of Pd(Ⅱ), the spirolactam ring was unfolded and a 1:1 metal-ligand complex formed, which can be used for "naked-eyes" detection. In addition, fluorescence imaging experiments of Pd²⁺ in HepG2 living cells showed its valuable application in biological systems.
- Rhodamine B,
- Palladium,
- Fluorescence probe,
- Living cell imaging
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