Citation: Vilas N. Mahire, Pramod P. Mahulikar. Facile one-pot clean synthesis of benzimidazole motifs: Exploration on bismuth nitrate accelerated subtle catalysis[J]. Chinese Chemical Letters, ;2015, 26(8): 983-987. doi: 10.1016/j.cclet.2015.04.012 shu

Facile one-pot clean synthesis of benzimidazole motifs: Exploration on bismuth nitrate accelerated subtle catalysis

Vilas N. Mahire ,
Pramod P. Mahulikar ^,

1.
School of Chemical Sciences, North Maharashtra University, Jalgaon 425 001, Maharashtra, India

Corresponding author: Pramod P. Mahulikar,
Received Date: 8 February 2015
Available Online: 19 March 2015
Fund Project: Authors are thankful to UGC, New Delhi, India for financial assistance under UGC-Major Research Project [No. 41-302/2012 (SR)] and SAIF, Panjab University, Chandigarh for NMR analysis. (SR)

In the present letter, an efficient, clean and one-pot synthesis of 2-substituted benzimidazole and 1,2-disubstituted benzimidazole derivatives has been explored by reacting o-phenylenediamine with aromatic aldehydes using bismuth nitrate as a catalyst in ethanol at ambient temperature. This methodology avails with faster reactions, excellent yield, mild reaction conditions, use of inexpensive and non-toxic catalyst compared to literature reported hitherto.
- Benzimidazole,
- o-Phenylenediamine,
- Aldehydes,
- Bismuth nitrate,
- Green chemistry
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