Citation: Goravanahalli M. Raghavendra, Chottanahalli S. Pavan Kumar, Gejjalagere P. Suresha, Kanchugarakoppal S. Rangappa, Kempegowda Mantelingu. T3P catalyzed one pot three-component synthesis of 2,3-disubstituted 3H-quinazolin-4-ones[J]. Chinese Chemical Letters, ;2015, 26(8): 963-968. doi: 10.1016/j.cclet.2015.03.037 shu

T3P catalyzed one pot three-component synthesis of 2,3-disubstituted 3H-quinazolin-4-ones

1.
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India

Corresponding author: Kanchugarakoppal S. Rangappa, Kempegowda Mantelingu,
Received Date: 25 December 2014
Available Online: 27 February 2015
Fund Project: Financial support from DST-Fast track, New Delhi (No. SERB/F/ 2013-14) is gratefully acknowledged. (No. SERB/F/ 2013-14)

An efficient methodology for the synthesis of 2,3-disubstituted 3H-quinazolin-4-ones is described via one-pot three component reaction from anthranilic acid using T3P as catalyst. Mild reaction conditions, short reaction time, broad functional group tolerance, easy isolation of products and good yields are main advantages of this protocol.
- 2,3-Disubstituted 3H-quinazolin-4-ones,
- T3P,
- Anthranilic acids,
- Aldehydes,
- Amines,
- DDQ
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