Citation: Li Wang, Zhen Zang, Yu-Fei Wang, Sheng-Xiong Huang, Pei Cao, Yong Zhao. Two new myrinsol diterpenoids from Euphorbia dracunculoides Lam.[J]. Chinese Chemical Letters, ;2015, 26(1): 121-123. doi: 10.1016/j.cclet.2014.08.005 shu

Two new myrinsol diterpenoids from Euphorbia dracunculoides Lam.

Li Wang ^a,b ,
Zhen Zang ^a ,
Yu-Fei Wang ^a ,
Sheng-Xiong Huang ^b ,
Pei Cao ^b,, ,
Yong Zhao ^a,,

1.
a College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, China;
2.
b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

Corresponding author: Pei Cao, Yong Zhao,
Received Date: 12 June 2014
Available Online: 25 August 2014
Fund Project: This work was financially supported by the National Natural Science Foundation of China (No. 21162044) (No. 21162044)

Two new myrinsol diterpenoids, euphordracunculins A (1) and B (2), together with three known analogues, euphorprolitherin B (3), proliferins A (4) and B (5), were isolated from the petroleum ether extract of the aerial parts of Euphorbia dracunculoides Lam. Their structures were elucidated by means of extensive spectroscopic analysis (NMR and ESI-MS) and comparison with data reported in the literature.
- Spurge,
- Euphorbia dracunculoides,
- Myrinsol,
- Diterpenoids
1. [1]
  [1] A.R. Jassbi, Chemistry and biological activity of secondary metabolites in Euphorbia from Iran, Phytochemistry 67 (2006) 1977-1984.
2. [2]
  [2] Q.W. Shi, X.H. Su, H. Kiyota, Chemical and pharmacological research of the plants in genus Euphorbia, Chem. Rev. 108 (2008) 4295-4327.
3. [3]
  [3] J. Xu, D.Q. Jin, P. Guo, et al., Three new myrsinol diterpenes from Euphorbia prolifera and their neuroprotective activities, Molecules 17 (2012) 9520-9528.
4. [4]
  [4] H. Haba, L. Marcourt, M. Benkhaled, C. Long, Minor ent-abietane diterpenoids from Euphorbia guyoniana, Nat. Prod. Commun. 8 (2013) 1519-1522.
5. [5]
  [5] S.A. Ivana, P. Milica, M.M. Slobodan, et al., Isolation and biological evaluation of jatrophane diterpenoids from Euphorbia dendroides, J. Nat. Prod. 74 (2011) 1613- 1620.
6. [6]
  [6] J.S. Ma, Y.Q. Cheng, Euphorbiaceae (3), Flora of China, Science Press, Beijing, 1997p. 118.
7. [7]
  [7] A.M. Zaghloul, New flavonoid glycosides from Euphorbia dracunculoides, Mans. J. Pharm. Sci. 9 (1993) 204-212.
8. [8]
  [8] R.K. Gautam, D.K. Mukharaya, Quercetin-3-O-β-D-glucopyranosyl (1→4)-O-α-L-rhamnopyranoside from Euphorbia dracuncoloids Lam. leaves, Nat. Acad. Sci. Lett. (India) 10 (1987) 95-96.
9. [9]
  [9] H.M. Chawla, K. Chakrabarty, S.S. Chibber, et al., Chemical components of Euphorbia dracunculoides Lam., Sci. Cult. 48 (1982) 203-205.
10. [10]
  [10] H.M. Chawla, K. Chakrabarty, S.S. Chibber, A.N. Kalia, N.C. Chaudhury, Daphnetin from Euphorbia dracunculoides fruits, Indian J. Pharm. Sci. 42 (1980) 138-139.
11. [11]
  [11] W.J. Zhang, D.F. Chen, A.J. Hou, Two novel myrinsol diterpenes from Euphorbia prolifera, Chin. Chem. Lett. 13 (2002) 744-747.
12. [12]
  [12] J. Li, L. Xu, F.P. Wang, New cytotoxic myrsinane-type diterpenes from Euphorbia prolifera, Helv. Chim. Acta 93 (2010) 746-752.
13. [13]
  [13] J. Xu, Y.Q. Guo, C.F. Xie, et al., Bioactive myrsinol diterpenoids from the roots of Euphorbia prolifera, J. Nat. Prod. 74 (2011) 2224-2230.
1. [1]
  Yingjie Wang , Peng Tang , Wenchao Tu , Qi Gao , Cuizhu Wang , Luying Tan , Lixin Zhao , Hongye Han , Liefeng Ma , Kouharu Otsuki , Weilie Xiao , Wenli Wang , Jinping Liu , Yong Li , Zhajun Zhan , Wei Li , Xianli Zhou , Ning Li . Highly anticipated natural diterpenoids as an important source of new drugs in 2013–2023. Chinese Chemical Letters, 2025, 36(1): 109955-. doi: 10.1016/j.cclet.2024.109955

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(675)
HTML views(22)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return