Citation: Jing-Wei Wan, Xue-Bing Ma, Rong-Xing He, Ming Li. An easy route to exotic 9-epimers of 9-amino-(9-deoxy) cinchona alkaloids with (8S, 9R) and (8R, 9S)-configurations through two inversions of configuration[J]. Chinese Chemical Letters, ;2014, 25(4): 557-560. doi: 10.1016/j.cclet.2013.12.008 shu

An easy route to exotic 9-epimers of 9-amino-(9-deoxy) cinchona alkaloids with (8S, 9R) and (8R, 9S)-configurations through two inversions of configuration

1.
College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China

Corresponding author: Xue-Bing Ma, Ming Li,
Received Date: 8 October 2013
Available Online: 28 November 2013

Four exotic chiral organocatalysts, 9-amino-(9-deoxy) cinchona alkaloids with (8S, 9R) and (8R, 9S)- configurations, were conveniently synthesized for the first time in 27-72% total yields through two conversions of configuration at the 9-stereogenic centers of commercially available cinchona alkaloids.
- Cinchona alkaloids,
- 9-Amino-(9-deoxy) cinchona alkaloids,
- Synthesis,
- Inversion of configuration
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