Citation: Ming Hui Xiang, Xiao Xu, Na Li, Ke An Li. Self-assembly of lysozyme on the surfaces of gold nanoparticles[J]. Chinese Chemical Letters, ;2011, 22(8): 973-976. doi: 10.1016/j.cclet.2011.01.022 shu

Self-assembly of lysozyme on the surfaces of gold nanoparticles

Ming Hui Xiang ^a, ,
Xiao Xu ^b ,
Na Li ^b ,
Ke An Li ^b

a School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China;
b College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

Received Date: 8 November 2010

Fund Project: This work was supported by the National Nature Sciences Foundation of China (Nos. 20475004, 90713013 & 20775004) and Shanghai Leading Academic Discipline Project (no. S30109).

The interaction of lysozyme (Lys) and gold nanoparticles was investigated via UV-vis absorption and resonance light-scattering method. There are some changes of the plasmon absorption and resonance light-scattering of gold nanoparticles that were observed via the addition of Lys. The normalized plasmon absorption and resonance light-scattering intensity with gold nanoparticles were both linear with 1-20 nmol/L Lys. A simple model about the component of the gold nanoparticles and Lys complex was established and the calculated result was fitted well in their concentration ratio. Furthermore, the activity analysis of Lys showed that the interaction was weak and nondestructive.
- Gold nanoparticles,
- Resonance light-scattering,
- Plasmon absorption,
- Lysozyme,
- Self-assemble
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