Citation: Li Ping Lin, Wei Qu, Jing Yu Liang. Triterpene saponins with XOD inhibitory activity from the roots of Ilex pubescens[J]. Chinese Chemical Letters, ;2011, 22(6): 697-700. doi: 10.1016/j.cclet.2010.12.045 shu

Triterpene saponins with XOD inhibitory activity from the roots of Ilex pubescens

Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China

Received Date: 29 September 2010

Fund Project: This work was financially supported by the Postgraduate Innovation Project of Jiangsu Province,China (No.CX09B_284Z)

A new triterpene saponin with 28-nor-urs-12(13),18(17)-dien-3β-ol as aglycone, named ilexsaponin C(1)was isolated from the roots of Ilex pubescens, together with three known saponins 2, 3 and 4.The structure of 1 was elucidated on the basis of spectral analysis including ID and 2D NMR and HR-ESI-MS.Saponins 1 and 4 exhibited significant XOD inhibitory activity in the test.
- Triterpene saponin,
- Ilex pubescens,
- Ilexsaponin C,
- Xantbine oxidase
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