Citation: Yan Jie Bao, Jun Jun Li, Yi Ting Wang Lei Yu, Lei Lou, Wei Ji Du, Zi Qiang Zhu, Hui Peng, Jian Zhong Zhu. Probing cytotoxicity of CdSe and CdSe/CdS quantum dots[J]. Chinese Chemical Letters, ;2011, 22(7): 843-846. doi: 10.1016/j.cclet.2010.12.008 shu

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

Institutes for Advanced Interdisciplinary Research, East China Normal University, Shanghai 200062, China

Received Date: 9 October 2010

Fund Project: The project is supported by National Natural Science Foundation of China (No.60976004) and Shanghai Municipal Commission for Science and Technology (No.09JC1405300).

Toxicities of CdSe and CdSe/CdS quantum dots (QDs) synthesized by ultrasound-assisted methods were investigated in vitro and in vivo. Five human cell lines were used to assess the cytotoxicity of as-prepared CdSe and CdSe/CdS by assays of MTT viability, red blood cell hemolysis, flow cytometry, and fluorescence imaging. The results show that these QDs may be cytotoxic by their influence in S and G2 phases in cell cycles. The cytotoxicity of QDs depends on both the physicochemical properties and related to target cells.
- Cytotoxicity,
- Quantum dots,
- CdSe,
- CdSe/CdS,
- Cell
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