Citation: Yellajyosula Lakshmi Narasimha Murthy, Nagalakshmi Karthikeyan, Govindh Boddeti, Bhagavathula S. Diwakar, E. Rajendra Singh. Design, synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl)[6H-indolo (2,3-b) quinoxalin-6-yl]methyl-amino) benzoate derivatives[J]. Chinese Chemical Letters, ;2011, 22(5): 567-570. doi: 10.1016/j.cclet.2010.10.055 shu

Design, synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl)[6H-indolo (2,3-b) quinoxalin-6-yl]methyl-amino) benzoate derivatives

Yellajyosula Lakshmi Narasimha Murthy ^a, ,
Nagalakshmi Karthikeyan ^a ,
Govindh Boddeti ^a ,
Bhagavathula S. Diwakar ^a ,
E. Rajendra Singh ^b

a Department of Organic Chemistry, Andhra University, Visakhapatnam 530003, India;
b DRDO-HQ, New Delhi 110011, India

Received Date: 13 September 2010

A series of new methyl-4-((substituted phenyl)[6H-indolo(2,3-b)quinoxalin-6yllmethylamino) benzoate derivatives have been synthesized and assayed for their antibacterial activity on 9 different bacterial strains.Among the screened compounds 2e-2g exhibited potent inhibitory activity compared to standard drug employed, worth further investigation.
- Isatin,
- Schiff base,
- Mannich base,
- Antibacterial activity
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