Citation: Shuang Hu, Zhuo Bin Shang, Yu Wang. Effect of dextran molecular weight on resonance light-scattering of quantum dots modified with dextran and concanavalin A[J]. Chinese Chemical Letters, ;2011, 22(2): 205-208. doi: 10.1016/j.cclet.2010.07.034 shu

Effect of dextran molecular weight on resonance light-scattering of quantum dots modified with dextran and concanavalin A

Shuang Hu ^a,b, ,
Zhuo Bin Shang ^a ,
Yu Wang ^a

a School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China;
b School of Pharmacy, Shanxi Medical University, Taiyuan 030001, China

Received Date: 2 June 2010

Fund Project: We thank the Natural Science Foundation of Shanxi Province (No. 2008011015-1) for financial support.

The reversible aggregation between dextran-conjugated CdSe quantum dots (Dex-CdSe-QDs) and concanavalin A (Con A) was explored based on the specific affinity of polysaccharide for Con A by resonance light-scattering technique. In this study, the aggregation of Dex-CdSe-QDs induced by Con A and sequential dissociation by glucose was determined over a wide range of dextran molecular mass (10-500 kDa). The results demonstrate that the sensitivity of lectin-dextran-modified-QDs interactions increase with dextran molecular mass, and an optimum dextran molecular mass is 500 kDa.
- Dextran molecular mass,
- CdSe quantum dots,
- Concanavalin A,
- Resonance light-scattering
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