Citation: Ming Hui Yang, Le Cai, Mei Hong Li, Xiang Hui Zeng, Ya Bin Yang, Zhong Tao Ding. Three new phenanthrenes from Monomeria barbata Lindl.[J]. Chinese Chemical Letters, ;2010, 21(3): 325-328. doi: 10.1016/j.cclet.2009.11.006
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Three new monophenanthrene compounds were isolated from an acetone extract of the tubers of Monomeria barbata Lindl. (Orchidaceae). Using spectroscopic methods, the structures of compounds 1-3 were determined as 1,4,7-trihydroxy-2-methoxy-9,10-dihydrophenanthrene (1), 1-(p-hydroxybenzoyl)-2-methoxy-4,7-dihydroxy-9,10-dihydrophenunthrene (2), 1,3,8-tri(p-hydroxybenzyl)-4-methoxy-phenanthrene-4,7-diol (3). These compounds showed cytotoxicities on four tumor cell lines (HepG2, HL-60, Skov-3, A431).
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Keywords:
- Monomeria barbara,
- Orchidaceae,
- Monophenanthrene,
- Cytotoxicity
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