Citation: Chao Liu, Fen Zhao, RuoYun Chen. A novel alkaloid from the fruiting bodies of Ganoderma sinense Zhao,Xu et Zhang[J]. Chinese Chemical Letters, ;2010, 21(2): 197-199. doi: 10.1016/j.cclet.2009.07.023 shu

A novel alkaloid from the fruiting bodies of Ganoderma sinense Zhao,Xu et Zhang

Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China

Received Date: 15 June 2009

Fund Project: This research program was supported by the Ministry of Science and Technology of the People's Republic of China (No. 2007Fy130100).

A new alkaloid,sinensine(1),had been isolated from the fruiting bodies of Ganoderma sinense Zhao,Xu et Zhang.Its structure was elucidated on the basis of ID and 2D spectral analysis.This alkaloid exhibited activity in protecting the injury induced by hydrogen peroxide oxidation on HUVEC,with EC₅₀ value 6.2 μmol/L.
- Alkaloid,
- Ganoderma sinense,
- Sinensine
1. [1]
  Jingping Hu , Jing Xu . Total synthesis of a putative yuzurimine-type Daphniphyllum alkaloid C₁₄–epi-deoxycalyciphylline H. Chinese Chemical Letters, 2024, 35(4): 108733-. doi: 10.1016/j.cclet.2023.108733

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