Citation:
Aamer Saeed. Microwave promoted synthesis of some N-(4-methyl-3-tolylthiazol-2(3H)-ylidene) substituted benzamides[J]. Chinese Chemical Letters,
;2009, 20(9): 1073-1076.
doi:
10.1016/j.cclet.2009.04.016
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N-(4-Methyl-3-tolylthiazol-2(3H)-ylidene) substituted benzamides (2a-o) were synthesized in good to excellent yields by the base-catalyzed direct cyclization of corresponding 1-tolyl-3-aryl thioureas (1a-o) with 2-bromoacetone through microwave irradiation in a solvent-free medium. Compared to traditional thermal heating, microwave irradiation provides a much more cleaner, efficient and faster method for synthesis of the title compounds.
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