Citation: Yun Peng Diao, Kun Li, Shan Shan Huang, Ke Xin Liu, Ting Guo Kang. A new compound from the fruit of Amorpha fruticosa and activity against acetaminophen-induced hepatotoxicity[J]. Chinese Chemical Letters, ;2009, 20(8): 942-944. doi: 10.1016/j.cclet.2009.03.039 shu

A new compound from the fruit of Amorpha fruticosa and activity against acetaminophen-induced hepatotoxicity

a College of Pharmacy, Dalian Medical University, Dalian 116044, China;
b College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116001, China;
c College of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, China

Received Date: 20 November 2008

Fund Project: This work was supported by the Science and Technology of Dalian (No.2008E11SF168).

A new isoflavone was obstained from the medicinal herb Amorpha fruticosa. It was elucidated asbenzopyran-12-one,1,4,10,11-tetrahydro-6'-[8'-(hydroxymethyl)ethenyl]-2,3-dimethoxy-8'-O-β-D-glucopyranosyl-O-α-D-arabinoside by spectroscopic methods including UV, IR, 1D NMR and 2D NMR techniques. And the activity against acetaminophen-induced hepatotoxicity of this compound was also studied, and found this compound can protect liver obviously from hepatotoxicity induced by acetaminophen (AAP).
- Amorpha fruticosa,
- Isoflavone,
- Activity against AAP
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