Citation: Yan Yang, Hong Gang Hu, Qing Jie Zhao, Shi Chong Yu, Zhi Gang Dan, Yan Zou, Qiu Ye Wu. One-pot synthesis of 7-bromo-1-[4-(1-cyano-1-methylethyl)]-phenyl-[1,2,4]-triazole-[4,3-a]-quinoxalin[J]. Chinese Chemical Letters, ;2009, 20(1): 52-54. doi: 10.1016/j.cclet.2008.10.019 shu

One-pot synthesis of 7-bromo-1-[4-(1-cyano-1-methylethyl)]-phenyl-[1,2,4]-triazole-[4,3-a]-quinoxalin

Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

Received Date: 15 July 2008

[1,2,4]-Triazole-[4,3-a]-quinoxaline is an important component of many drugs. The yield of the reported methods for triazole cyclization step was usually as low as 20%. In this article, the triazole cyclization step was successfully done by using microwave method with a high yield of 75% for the first time.
- [1,2,4]-Triazole-[4,3-a]-quinoxaline,
- Microwave,
- Synthesis
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