Citation: Jian Feng Zhou, Gui Xia Gong, Feng Xia Zhu, San Jun Zhi. Microwave promoted one-pot synthesis of 3-(2'-amino-3'-cyano-4'-arylpyrid-6'-yl) coumarins[J]. Chinese Chemical Letters, ;2009, 20(1): 37-39. doi: 10.1016/j.cclet.2008.10.006 shu

Microwave promoted one-pot synthesis of 3-(2'-amino-3'-cyano-4'-arylpyrid-6'-yl) coumarins

a Department of Chemistry, Huaiyin Teachers College, Jiangsu Key Laboratory for Chemistry of Low-DimensionalMaterials, Huaian 223300, China;
b School of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University, Suzhou 215123, China

Received Date: 18 June 2008

Fund Project: We thank the Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials for financial support (No. JSKC07041).

A facile procedure for the synthesis of 3-(2'-amino-3'-cyano-4'-arylpyrid-6'-yl) coumarins are being reported starting from 3-acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, ¹H NMR,and mass spectral data.
- 3-(2'-Amino-3'-cyano-4'-arylpyrid-6'-yl)coumarin,
- Aromatic aldehyde,
- 3-Acetylcoumarin,
- Microwave irradiation
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