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Citation:
Xiu Lan Xin, Rong Lan, Jian Huang, Xiao Jie Wang, Jing Ming Jia. A new cytotoxic bufadienolide from Chinese medicine Chansu[J]. Chinese Chemical Letters,
;2008, 19(12): 1445-1446.
doi:
10.1016/j.cclet.2008.09.037
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A new cytotoxic bufadienolide was isolated from the traditional Chinese medicine-Chansu. The structure of new compound was elucidated on the basis of spectral methods including 2D NMR. And it showed strong in vitro eytotoxic activity against Hela cells with IC50 of 8.06×10-2 μmol/L.
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Keywords:
- Bufadienolide,
- Steroid,
- Cytotoxicity,
- Chansu
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