Citation: Wei Hua, Qing Chun Zhao, Jia Yang, Guo Bing Shi, Li Jun Wu, Tao Guo. Two new benzofuran lignan glycosides from Gelsemium elegans[J]. Chinese Chemical Letters, ;2008, 19(11): 1327-1329. doi: 10.1016/j.cclet.2008.09.012 shu

Two new benzofuran lignan glycosides from Gelsemium elegans

Wei Hua ^a,b, ,
Qing Chun Zhao ^b ,
Jia Yang ^a ,
Guo Bing Shi ^b ,
Li Jun Wu ^a ,
Tao Guo ^b

a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;
b Department of Pharmacy, Shenyang Northern Hospital, Shenyang 110016, China

Received Date: 19 May 2008

Fund Project: We wish to thank Professor Qi Shi Sun of Shenyang Pharmaceutical University,for identification of the plant materials. The Project was sponsored by the Scientific Research Foundation for the doctoral Scholars (Q.C. Zhao,No. 20031040),Liaoning,China.

Two new benzofuran lignan glycosides,gelsemiunoside A and B,were isolated from the whole plant of Gelsemium elegans Benth.Their structures were elucidated on the basis of spectroscopic evidence.Furthermore,gelsemiunoside A and B were shown a potent cytotoxic activity by suppressing the proliferation of A375-S2 cells.
- Gelsemium elegans,
- Benzofuran ligaan glycoside,
- Gelsemiunoside A,
- Gelsemiunoside B
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