Two new lignans from Dipteronia dyeriana

Rong Guo ^a,b, ,
Min Luo ^c ,
Chun Lin Long ^a ,
Ma Lin Li ^c ,
Zhi Qin Ouyang ^d ,
Yi Ping Zhou ^c ,
Yue Hu Wang ^a ,
Xing Yu Li ^a,b ,
Ya Na Shi ^a,b

a Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;Yunnan Agricultural University, Kunming 650201, China;
b Yunnan Agricultural University, Kunming 650201, China;
c Yunnan Laboratory of Pharmacology for Natural Products, Kunming Medical College, Kunming 650031, China;
d Yunnan Introduction & Propagation Center for Rare & Endangered Plants, Kunming 650032, China

Received Date: 7 March 2008

Fund Project: This work was financially supported by grants from the Ministry of Science and Technology of China (2005DKA21006) and the Knowledge Innovation Project of Chinese Academy of Sciences.

A new sesquilignan,7',8'-didehydroherpetotriol(1),and a new lignan glycoside,(+)-isolariciresinol-9'-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(2),were isolated from the branches of Dipteronia dyeriana.Their structures were elucidated by spectroscopic methods and chemical evidence.Compound 1 possessed inhibitory activity against human leukaemia K562 cells with an IC₅₀ value of 39 μmol/L.

Two new lignans from Dipteronia dyeriana

Metrics

通讯作者: 陈斌, bchen63@163.com