Citation: Foad Kazemi, Ali Reza Kiasat, Ebrahim Sarvestani. Practical reduction of imines by NaB H₄/alumina under solvent-free conditions: An efficient route to secondary amine[J]. Chinese Chemical Letters, ;2008, 19(10): 1167-1170. doi: 10.1016/j.cclet.2008.06.043 shu

Practical reduction of imines by NaB H₄/alumina under solvent-free conditions: An efficient route to secondary amine

a Institute for Advanced Studies in Basic Sciences(IASBS), Zanjan 45195, Iran;
b Chemistry Department, College of Science, Shahid Chamran University, Ahvaz 61357-4-3169, Iran

Received Date: 27 March 2008

Fund Project: Partial support for this work by Chamran University Research Council are gratefully acknowledged.

Sodium borohydride supported on alumina reduces imines to the corresponding secondary amines in high to excellent isolated yields under solvent-free conditions.Noteworthy is that highly chemoselective reactions were achieved in the presence of other functional groups such as halogen,nitro,and cyano groups.
- Imine,
- Secondary amine,
- Solvent free,
- Reduction,
- Sodium borohydride
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