Citation: Jin Hui Yang, Yan Min Zhao, Cong Bin Ji. First total synthesis of (±)-abyssinoflavanone V[J]. Chinese Chemical Letters, ;2008, 19(6): 658-660. doi: 10.1016/j.cclet.2008.04.019
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The total synthesis of (±)-abyssinoflavanone V was first achieved through C-prenylation, selective protection of phenolic hydroxyl group, aldol condensation, cyclization and deprotection starting from cheap 4-hydroxybenzaldehyde and 2,4,6-trihydroxyacetophenone, with total yield 24%. All structures of new compounds were confirmed by IR,1H NMR and MS.
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Keywords:
- Abyssinoflavanone V,
- Flavanone,
- Isoprenylflavanoids,
- Total synthesis
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