Citation: Chen Xi Zhang, Li Jing Fang, Fu Qiang Bi, Yu Lin Li. An enantioselective formal synthesis of (-)-thujopsene[J]. Chinese Chemical Letters, ;2008, 19(3): 256-258. doi: 10.1016/j.cclet.2008.01.009 shu

An enantioselective formal synthesis of (-)-thujopsene

State Key Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000, China

Received Date: 15 October 2007

Fund Project: This work was financially supported by the National Natural Science Foundation of China (No. 20072012) and the Special Research Grant for Doctoral Sites in Chinese Universities (No. 20010730001).

Dihydromayurone (3), a key intermediate to synthesize (-)-thujopsene (1), was efficient enantiocontrolled synthesized from (+)-dihydrocarvone through 9 steps in an overall yield of 19.3%. The key step was the Simmons-Smith reaction.
- Thujopsene,
- Dihydromayurone,
- Synthesis,
- Dihydrocarvone,
- Simmons-Smith reaction
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