Citation: Zhi Bo Li, Yong Ming Bao, Hong Bo Chen, Jing Yun Wang, Jie Han Hu, Li Jia An. A cytotoxic compound from the leaves of Juglans mandshurica[J]. Chinese Chemical Letters, ;2007, 18(7): 846-848. doi: 10.1016/j.cclet.2007.05.043 shu

A cytotoxic compound from the leaves of Juglans mandshurica

a Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian 116024, China;
b School of Chemical Engineering, Dalian University of Technology, Dalian 116024, China;
c Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116011, China

Received Date: 12 March 2007

From Juglans mandshurica leaves, a new quinone compound was isolated through bioassay-guided fractionation. The structure elucidation of the compound was established based on spectroscopic studies, notably of the 2D NMR spectra. The compound exhibited moderate cytotoxic activities against Hela, MCF-7, BGC823 and 3T3-Llcell lines with IC₅₀ ranges from 7.5 to 26.8 μmol/L.
- Juglans mandshurica,
- p-Hydroxymethoxybenzobijuglone,
- Cytotoxicity
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