Citation: Qiao Song, Zhi Luo, Xinming Tong, Yi Du, Yanbin Huang. Glutathione as the End Capper for Cyclodextrin/PEG Polyrotaxanes[J]. Chinese Journal of Polymer Science, ;2014, 32(8): 1003-1009. doi: 10.1007/s10118-014-1477-y shu

Glutathione as the End Capper for Cyclodextrin/PEG Polyrotaxanes

Qiao Song ¹ ,
Zhi Luo ¹ ,
Xinming Tong ¹ ,
Yi Du ¹ ,
Yanbin Huang ¹

1.
Department of Chemical Engineering, Tsinghua University, Beijing 100084, China

Received Date: 13 November 2013
Revised Date: 11 January 2014

Fund Project: This work was financially supported by the National Natural Science Foundation of China (No. 21004038)

A facile one-pot synthesis of a-cyclodextrin-based polyrotaxane (PR) in aqueous solution is reported, where the peptide glutathione was used as the end-capping agent and the thiol-ene Michael addition was used as the end-capping reaction. Both polyrotaxanes with low threading ratio and high threading ratio were successfully obtained. In contrast to the conventionally used multiple-step synthesis methods and hydrophobic end cappers, this one-pot aqueous synthesis as well as the biocompatibility of the end-capping agent could result in a much more biocompatible PR to be used as biomaterials.
- Polyrotaxane,
- Cyclodextrin,
- Polyethylene glycol,
- Glutathione,
- Biocompatibility
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
24. [24]
25. [25]
26. [26]
27. [27]
28. [28]
29. [29]
30. [30]
31. [31]
1. [1]
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2. [2]
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3. [3]
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5. [5]
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6. [6]
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8. [8]
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9. [9]
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