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2006 Volume 17 Issue 2
2006, 17(2): 143-146
Abstract:
The asymmetric ring-opening of epoxides with dithiophosphorus acids catalyzed by a (salen)Ti(Ⅳ) complex formed in situ from the reaction of Ti(OPr-i)4 and the chiral Schiff base derived from (1R, 2R)-(+)-diaminocyclohexane was realized. The resulting products were obtained with low to good enantioselectivity (up to 73% ee).
The asymmetric ring-opening of epoxides with dithiophosphorus acids catalyzed by a (salen)Ti(Ⅳ) complex formed in situ from the reaction of Ti(OPr-i)4 and the chiral Schiff base derived from (1R, 2R)-(+)-diaminocyclohexane was realized. The resulting products were obtained with low to good enantioselectivity (up to 73% ee).
2006, 17(2): 147-149
Abstract:
An efficient total synthesis of 6-oxodendrolasinolide 1, a new farnesane-based homosesquiterpene lactone, starting from geraniol 2 through twelve steps is described. Our work involved two key steps: (1) regioselective alkylation of the anion of vinyldithian 5 with allylic chloride 31, (2) Corey's oxidative lactionization method2.
An efficient total synthesis of 6-oxodendrolasinolide 1, a new farnesane-based homosesquiterpene lactone, starting from geraniol 2 through twelve steps is described. Our work involved two key steps: (1) regioselective alkylation of the anion of vinyldithian 5 with allylic chloride 31, (2) Corey's oxidative lactionization method2.
2006, 17(2): 150-152
Abstract:
An efficient and green method for the synthesis of 1, 4-dihydropyridine derivatives mediated in an ionic liquid, [bmim][BF4], through a four-component condensation process of aldehydes, 1, 3-dione, Meldrum's acid and ammonium acetate is disclosed in this paper.
An efficient and green method for the synthesis of 1, 4-dihydropyridine derivatives mediated in an ionic liquid, [bmim][BF4], through a four-component condensation process of aldehydes, 1, 3-dione, Meldrum's acid and ammonium acetate is disclosed in this paper.
2006, 17(2): 153-155
Abstract:
The synthesis of novel 1-arylsulfonyl -4-(1'-N-2', 3', 4', 6'-tetra-O-acetyl-β-D-glucopyranosyl) thiosemicarbazides via condensation of 2, 3, 4, 6-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate with substituted phenylsulfonyl hydrazines was described. Their structures and physical properties were confirmed by 1H NMR, 13C NMR spectra, elemental analysis and MS.
The synthesis of novel 1-arylsulfonyl -4-(1'-N-2', 3', 4', 6'-tetra-O-acetyl-β-D-glucopyranosyl) thiosemicarbazides via condensation of 2, 3, 4, 6-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate with substituted phenylsulfonyl hydrazines was described. Their structures and physical properties were confirmed by 1H NMR, 13C NMR spectra, elemental analysis and MS.
2006, 17(2): 156-158
Abstract:
Three 2-oxoglutaric acid analogues were synthesized. Their interaction with factorinhibiting hypoxia-inducible factor (FIH) was studied using LC-MS method. The results show that hydrophobic substitutes of 2-oxoglutaric acids have great influence on their inhibitor activity.
Three 2-oxoglutaric acid analogues were synthesized. Their interaction with factorinhibiting hypoxia-inducible factor (FIH) was studied using LC-MS method. The results show that hydrophobic substitutes of 2-oxoglutaric acids have great influence on their inhibitor activity.
2006, 17(2): 159-162
Abstract:
A solid-phase synthesis of 1α-hydroxylation of 5, 6-trans-vitamin D3 8 is described.The solid phase resin acts as a special protecting group, which gives a higher stereoselectivity in oxidation step than classical protecting groups. The stereochemistry control is favored by using high crosslinkage polymer support in a poor solvent. This work may be of benefit to the synthesis of vitamin D system.
A solid-phase synthesis of 1α-hydroxylation of 5, 6-trans-vitamin D3 8 is described.The solid phase resin acts as a special protecting group, which gives a higher stereoselectivity in oxidation step than classical protecting groups. The stereochemistry control is favored by using high crosslinkage polymer support in a poor solvent. This work may be of benefit to the synthesis of vitamin D system.
2006, 17(2): 163-164
Abstract:
A first facile total synthesis of 12-hydroxy-13-methylpodocarpa-9, 11, 13-trien-3-one 9 was accomplished via a strategy of AC→ABC. In the synthetic process, compound 5 was synthesized through Reimer-Teimann reaction, followed by methylation, reduction, dehydration, addition to ethylene epoxide and chlorination. The target compound 9 was finally obtained through the condensation of Grignard reagent of compound 5 with 6, followed by intramolecular cyclization, reduction and demethylation.
A first facile total synthesis of 12-hydroxy-13-methylpodocarpa-9, 11, 13-trien-3-one 9 was accomplished via a strategy of AC→ABC. In the synthetic process, compound 5 was synthesized through Reimer-Teimann reaction, followed by methylation, reduction, dehydration, addition to ethylene epoxide and chlorination. The target compound 9 was finally obtained through the condensation of Grignard reagent of compound 5 with 6, followed by intramolecular cyclization, reduction and demethylation.
2006, 17(2): 165-168
Abstract:
Grignard additions to a quinoxalinium salt were studied. Depending on the ratio of the reagents and reaction temperature, 1, 2, 3, 4-tetrahydroquinoxaline and 1, 2-dihydroquinoxaline derivatives could be resulted selectively.
Grignard additions to a quinoxalinium salt were studied. Depending on the ratio of the reagents and reaction temperature, 1, 2, 3, 4-tetrahydroquinoxaline and 1, 2-dihydroquinoxaline derivatives could be resulted selectively.
2006, 17(2): 169-172
Abstract:
Multiester-appended imidazolium ionic liquids were synthesized in a quatemization reaction between the imidazole derivatives carrying single or double esters and ethyl chloroacetate or bromoethane. Multicarboxylic-appended imidazolium ionic liquids were achieved from the hydrolysis of the corresponding ionic liquids. The influences of multifunctional groups on the transition temperatures and viscosity of these new ionic liquids were investigated.
Multiester-appended imidazolium ionic liquids were synthesized in a quatemization reaction between the imidazole derivatives carrying single or double esters and ethyl chloroacetate or bromoethane. Multicarboxylic-appended imidazolium ionic liquids were achieved from the hydrolysis of the corresponding ionic liquids. The influences of multifunctional groups on the transition temperatures and viscosity of these new ionic liquids were investigated.
2006, 17(2): 173-176
Abstract:
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl)4-oxo-4-[2-(lactobionylamido)ethylamido]butanoate 6 was synthesized. Its chemical structure was characterized by IR, ESI-MS, 13C NMR, 1H NMR. Doxorubicin entrapped in the liposomes containing 10% mol/mol 6 was rapidly accumulated in liver and mainly uptake by parenchymal cells in mice.
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl)4-oxo-4-[2-(lactobionylamido)ethylamido]butanoate 6 was synthesized. Its chemical structure was characterized by IR, ESI-MS, 13C NMR, 1H NMR. Doxorubicin entrapped in the liposomes containing 10% mol/mol 6 was rapidly accumulated in liver and mainly uptake by parenchymal cells in mice.
2006, 17(2): 177-179
Abstract:
A convenient and effective method for synthesis of L-phosphinothricin was described.The highlight was involved in a simple access to the key intermediate L-2-amino-4-chlorobutyric acid derivative from the inexpensive L-methionine.
A convenient and effective method for synthesis of L-phosphinothricin was described.The highlight was involved in a simple access to the key intermediate L-2-amino-4-chlorobutyric acid derivative from the inexpensive L-methionine.
2006, 17(2): 180-182
Abstract:
A novel approach to the synthesis of ozagrel is described. The target compound isconveniently prepared from the commercially available material, 1, 1-carboxyldiimidazole (CDI)through the condensation and hydrolyzation.
A novel approach to the synthesis of ozagrel is described. The target compound isconveniently prepared from the commercially available material, 1, 1-carboxyldiimidazole (CDI)through the condensation and hydrolyzation.
2006, 17(2): 183-186
Abstract:
One of the analogues of icogenin, a natural furostanol saponin showing strong cytotoxic effect on cancer cell, was first synthesized via convergent strategy by using diosgenin and available monosaccharides as starting materials.
One of the analogues of icogenin, a natural furostanol saponin showing strong cytotoxic effect on cancer cell, was first synthesized via convergent strategy by using diosgenin and available monosaccharides as starting materials.
2006, 17(2): 187-190
Abstract:
The nine new 11H-indeno[1, 2-b]quinolines were synthesized in high yield with sodium ethoxide as a catalyst via the Friedänder condensation reaction. The possible reaction mechanism was proposed.
The nine new 11H-indeno[1, 2-b]quinolines were synthesized in high yield with sodium ethoxide as a catalyst via the Friedänder condensation reaction. The possible reaction mechanism was proposed.
2006, 17(2): 191-194
Abstract:
Poly (hydroxyethyl, octanediamine)-DL-aspartamide (PHOA) hydrogels were prepared by adding mixture of 1, 8-octanediamine and ethanolamine to PA in DMF at room temperature. The properties of the hydrogels were investigated by FT-IR, 1HNMR, TGA and cell culture assay.
Poly (hydroxyethyl, octanediamine)-DL-aspartamide (PHOA) hydrogels were prepared by adding mixture of 1, 8-octanediamine and ethanolamine to PA in DMF at room temperature. The properties of the hydrogels were investigated by FT-IR, 1HNMR, TGA and cell culture assay.
2006, 17(2): 195-197
Abstract:
Three new triterpenes, 3β, 21α-dihydroxylupen-18(19)-en (1), 3β, 25-dihydroxytirucalla7, 23(24)-dien (2), and 21α-hydroxy-19α-hydrogentaraxasterol-20(30)-en (3) were obtained from an ethyl acetate extract of the whole plant of Siyekucai (Ixeris chinensis). The structures of 1-3 were determined by spectroscopic methods (EIMS, IR, 1D and 2D NMR).
Three new triterpenes, 3β, 21α-dihydroxylupen-18(19)-en (1), 3β, 25-dihydroxytirucalla7, 23(24)-dien (2), and 21α-hydroxy-19α-hydrogentaraxasterol-20(30)-en (3) were obtained from an ethyl acetate extract of the whole plant of Siyekucai (Ixeris chinensis). The structures of 1-3 were determined by spectroscopic methods (EIMS, IR, 1D and 2D NMR).
2006, 17(2): 198-200
Abstract:
A new hemiterpenoid, (+)-(2R,3S)-2-chloro-3-hydroxy-3-methyl-γ-buty-rolactone was isolated from the leaves of Prinsepia utilis Royle. Its structure was elucidated by spectroscopic methods and X-ray crystallographic analysis.
A new hemiterpenoid, (+)-(2R,3S)-2-chloro-3-hydroxy-3-methyl-γ-buty-rolactone was isolated from the leaves of Prinsepia utilis Royle. Its structure was elucidated by spectroscopic methods and X-ray crystallographic analysis.
2006, 17(2): 201-203
Abstract:
A new jatrophane diterpenoid ester (2S, 3S, 4R, 5R, 7S, 8R, 13R, 15R)-3, 5, 7, 8, 15-pentaacetoxy-9, 14-dioxojatropha-6(17), 11E-diene was isolated from the whole plant of Euphorbia turczaninowii Kar. & Kir.. Its structure was characterized by spectral analysis and confirmed by X-ray crystallographic analysis.
A new jatrophane diterpenoid ester (2S, 3S, 4R, 5R, 7S, 8R, 13R, 15R)-3, 5, 7, 8, 15-pentaacetoxy-9, 14-dioxojatropha-6(17), 11E-diene was isolated from the whole plant of Euphorbia turczaninowii Kar. & Kir.. Its structure was characterized by spectral analysis and confirmed by X-ray crystallographic analysis.
2006, 17(2): 204-206
Abstract:
Two new triterpenoids, lanost-9(11), 23Z(24)-diene-3β, 25-diol (1) and lanost-9(11), 25-diene-3β, 24-diol (2) were isolated from Mulgedium tataricum L. Their structures were elucidated by spectral methods.
Two new triterpenoids, lanost-9(11), 23Z(24)-diene-3β, 25-diol (1) and lanost-9(11), 25-diene-3β, 24-diol (2) were isolated from Mulgedium tataricum L. Their structures were elucidated by spectral methods.
2006, 17(2): 207-210
Abstract:
A novel phenylpropanoid-substituted catechin glycoside glabraoside A 1 and a new dihydrochalcone 3'-(7"-allylphenyl)-2', 4', 4"-trihydroxy-6'-methoxydihydrochalcone 2 were isolated from the herbs of Sarcandra glabra. Their structures were elucidated on the basis of spectroscopic analyses and chiroptical methods.
A novel phenylpropanoid-substituted catechin glycoside glabraoside A 1 and a new dihydrochalcone 3'-(7"-allylphenyl)-2', 4', 4"-trihydroxy-6'-methoxydihydrochalcone 2 were isolated from the herbs of Sarcandra glabra. Their structures were elucidated on the basis of spectroscopic analyses and chiroptical methods.
2006, 17(2): 211-214
Abstract:
A new triterpenoid saponin, 21β-angeloylprotoaescigenin-3β-O-[α-L-rhamnopyranosyl(1-3)]β-D-glucopyranosiduronic acid 1, was isolated from the seeds of Aesculus assamica Griff. Its structure was elucidated on the basis of spectroscopic data analysis.
A new triterpenoid saponin, 21β-angeloylprotoaescigenin-3β-O-[α-L-rhamnopyranosyl(1-3)]β-D-glucopyranosiduronic acid 1, was isolated from the seeds of Aesculus assamica Griff. Its structure was elucidated on the basis of spectroscopic data analysis.
2006, 17(2): 215-217
Abstract:
Two new eremophilenolides were isolated from the roots of Ligularia muliensis. Their structures were elucidated on the basis of the spectroscopic analysis as 6β-acetoxy-8β-hydroxyl-eremophil-7(11)-en-12, 8α-olide 1 and 6α-hydroxy-8βH-eremophil-7(11)-en-12, 8α-olide 2.
Two new eremophilenolides were isolated from the roots of Ligularia muliensis. Their structures were elucidated on the basis of the spectroscopic analysis as 6β-acetoxy-8β-hydroxyl-eremophil-7(11)-en-12, 8α-olide 1 and 6α-hydroxy-8βH-eremophil-7(11)-en-12, 8α-olide 2.
2006, 17(2): 218-220
Abstract:
Two new dihydroflavonoids were obtained from the traditional Chinese medicinal herb Patrinia villosa Juss. Their structures were elucidated as (2S)-5, 7, 2', 6'-tetrahydroxy-6, 8-di (γ, γ-dimethylallyl) flavanone (1) and (2S)-5, 7, 2', 6'-tetrahydroxy-6-lavandulylated flavanone (2) by spectroscopic methods including UV, IR, HR-TOF-MS, 1D NMR and 2D NMR techniques.
Two new dihydroflavonoids were obtained from the traditional Chinese medicinal herb Patrinia villosa Juss. Their structures were elucidated as (2S)-5, 7, 2', 6'-tetrahydroxy-6, 8-di (γ, γ-dimethylallyl) flavanone (1) and (2S)-5, 7, 2', 6'-tetrahydroxy-6-lavandulylated flavanone (2) by spectroscopic methods including UV, IR, HR-TOF-MS, 1D NMR and 2D NMR techniques.
2006, 17(2): 221-224
Abstract:
Mercaptopropyl groups were grafted onto the pore walls of mesoporous molecular sieves MCM-48. The pore structures were characterized by powder X-ray diffraction and N2 adsorption analysis. Elemental analysis confirmed that the material with high organic moiety (2.2 mmol/g) had been obtained. 13C MAS NMR verified the tethered organic groups. The thiol-functionalized MCM-48 showed effective capture of mercury ions, and all of the organic ligands were accessible for the binding of mercury ions.
Mercaptopropyl groups were grafted onto the pore walls of mesoporous molecular sieves MCM-48. The pore structures were characterized by powder X-ray diffraction and N2 adsorption analysis. Elemental analysis confirmed that the material with high organic moiety (2.2 mmol/g) had been obtained. 13C MAS NMR verified the tethered organic groups. The thiol-functionalized MCM-48 showed effective capture of mercury ions, and all of the organic ligands were accessible for the binding of mercury ions.
2006, 17(2): 225-227
Abstract:
The adsorptive and electrochemical behaviour of phoxim on a hanging mercury drop electrode were explored in NH3·H2O-NH4CL buffer by using cyclic and linear sweep voltmmery The procedure was successfully applied for the assay of phoxim in vegetable and fruit samples.
The adsorptive and electrochemical behaviour of phoxim on a hanging mercury drop electrode were explored in NH3·H2O-NH4CL buffer by using cyclic and linear sweep voltmmery The procedure was successfully applied for the assay of phoxim in vegetable and fruit samples.
2006, 17(2): 228-230
Abstract:
By bridging 1, 3:4, 6-bis(3, 6-dihydroxy-1, 2-xylylene)tetrahydro-3a, 6a-diphenyl imidazo[4, 5]-imidazole-2, 5(1H, 3H)-dione 1 with S(CH2CH2OCOCH2Cl)2, thiacrown molecular basket 2c was prepared for the first time. It was found that the compound exhibited very poor affinity towards alkali metal ions but high extracting selectivity towards silver ion.
By bridging 1, 3:4, 6-bis(3, 6-dihydroxy-1, 2-xylylene)tetrahydro-3a, 6a-diphenyl imidazo[4, 5]-imidazole-2, 5(1H, 3H)-dione 1 with S(CH2CH2OCOCH2Cl)2, thiacrown molecular basket 2c was prepared for the first time. It was found that the compound exhibited very poor affinity towards alkali metal ions but high extracting selectivity towards silver ion.
2006, 17(2): 231-234
Abstract:
Ionic liquid (1-ethyl-3-methylimidazolium tetrafluoroborate, 1E-3MI-TFB) and HP-β-CD as modifier was added to the buffer to separate hyperoside, luteolin and chlorogenic acid.Experiments explored the effect of concentration of 1E-3MI-TFB and HP-β-CD on separation.The results indicated that 1.0 mmol/L HP-β-CD and 1‰ (v/v) 1E-3MI-TFB added to the buffer simultaneous y could achieve a good compromise of resolution and analysis time. Capillary experiments and UV spectra indicated that there was interaction between 1E-3MI-TFB and analytes.
Ionic liquid (1-ethyl-3-methylimidazolium tetrafluoroborate, 1E-3MI-TFB) and HP-β-CD as modifier was added to the buffer to separate hyperoside, luteolin and chlorogenic acid.Experiments explored the effect of concentration of 1E-3MI-TFB and HP-β-CD on separation.The results indicated that 1.0 mmol/L HP-β-CD and 1‰ (v/v) 1E-3MI-TFB added to the buffer simultaneous y could achieve a good compromise of resolution and analysis time. Capillary experiments and UV spectra indicated that there was interaction between 1E-3MI-TFB and analytes.
2006, 17(2): 235-238
Abstract:
A novel electrochemical immunoassay for cardiac troponin I (cTnI) combining the concepts of the dual monoclonal antibody "sandwich" principle, the silver enhancement on the nano-gold particle, and the SBA-15 mesoporous modified carbon paste electrode (SBA-MCPE) is described. Four main steps were carried out to obtain the analytical signal, i.e., electrode preparation, immunoreaction, silver enhancement, and anodic stripping voltammetric detection.A linear relationship between the anodic stripping peak current and concentration of cTnI from 0.5 to 5.0 ng/mL and a limit of detection of 0.2 ng/mL of cTnI were obtained.
A novel electrochemical immunoassay for cardiac troponin I (cTnI) combining the concepts of the dual monoclonal antibody "sandwich" principle, the silver enhancement on the nano-gold particle, and the SBA-15 mesoporous modified carbon paste electrode (SBA-MCPE) is described. Four main steps were carried out to obtain the analytical signal, i.e., electrode preparation, immunoreaction, silver enhancement, and anodic stripping voltammetric detection.A linear relationship between the anodic stripping peak current and concentration of cTnI from 0.5 to 5.0 ng/mL and a limit of detection of 0.2 ng/mL of cTnI were obtained.
2006, 17(2): 239-242
Abstract:
Amphiphilic copolymer of 5-benzyloxytrimethylene carbonate (BTMC) with poly (vinyl pyrrolidone) (PVP) was successfully synthesized using immobilized porcine pancreas lipase (IPPL) or SnOct2 as catalyst. Hydroxyl terminated PVP, synthesized with 2-mercaptoethanol as a chain transfer reagent, was employed as a macroinitiator. The resulting copolymers were characterized by GPC, 1H NMR and IR. Increasing the BTMC/PVP-OH feed ratio ([B]/[P])resulted in the increase of Mn of corresponding copolymers and the decrease of Mw/Mn.Immobilized enzyme has comparable catalytic activity to SnOct2 for the copolymerization.
Amphiphilic copolymer of 5-benzyloxytrimethylene carbonate (BTMC) with poly (vinyl pyrrolidone) (PVP) was successfully synthesized using immobilized porcine pancreas lipase (IPPL) or SnOct2 as catalyst. Hydroxyl terminated PVP, synthesized with 2-mercaptoethanol as a chain transfer reagent, was employed as a macroinitiator. The resulting copolymers were characterized by GPC, 1H NMR and IR. Increasing the BTMC/PVP-OH feed ratio ([B]/[P])resulted in the increase of Mn of corresponding copolymers and the decrease of Mw/Mn.Immobilized enzyme has comparable catalytic activity to SnOct2 for the copolymerization.
2006, 17(2): 243-246
Abstract:
Schiff base ligand (HL) derived from 4-hexylaniline with isatin (1H-indole-2, 3-dione)and its complexes with Cu(Ⅱ), Ni(Ⅱ) were prepared and characterized by analytical, spectroscopic (IR, UV-Vis, Mass) techniques, electrical conductivity, magnetic and thermal measurements. The crystal and molecular structure of [Cu(HL)2Cl2] was determined by a single-crystal X-ray diffraction study. The molecular structure of the title compound has an inversion center on the Cu atom.
Schiff base ligand (HL) derived from 4-hexylaniline with isatin (1H-indole-2, 3-dione)and its complexes with Cu(Ⅱ), Ni(Ⅱ) were prepared and characterized by analytical, spectroscopic (IR, UV-Vis, Mass) techniques, electrical conductivity, magnetic and thermal measurements. The crystal and molecular structure of [Cu(HL)2Cl2] was determined by a single-crystal X-ray diffraction study. The molecular structure of the title compound has an inversion center on the Cu atom.
2006, 17(2): 247-250
Abstract:
The polymerization of the inverse microemulsions composed of methyl methacrylate, acrylic acid, sodium dodecyl sulfate and water was monitored by refractometer, conductometer and time-resolved light scattering device. The results showed that refractive index, conductivity or intensity distribution of scattered light changed along with polymerization, and different processes of polymerization could be identified.
The polymerization of the inverse microemulsions composed of methyl methacrylate, acrylic acid, sodium dodecyl sulfate and water was monitored by refractometer, conductometer and time-resolved light scattering device. The results showed that refractive index, conductivity or intensity distribution of scattered light changed along with polymerization, and different processes of polymerization could be identified.
2006, 17(2): 251-252
Abstract:
A general method for modification of nano-alumina surface is investigated using Michael addition reaction with α, β-unsaturated carbonyl compounds.
A general method for modification of nano-alumina surface is investigated using Michael addition reaction with α, β-unsaturated carbonyl compounds.
2006, 17(2): 253-254
Abstract:
The interaction between calf thymus DNA (ctDNA) and Pd (Ⅱ) meso-tetrakis(4-N-methyl pyridiniumyl) porphyrin (Pd-TMPyP) was investigated by steady solid-substrate room temperature phosphorescence (SS-RTP). The SS-RTP intensity and lifetime of Pd-TMPyP enhanced with the increasing ctDNA. The anion quenching experiment of Pd-TMPyP indicated that Pd-TMPyP intercalated into ctDNA, which was also approved by UV-Vis spectra.
The interaction between calf thymus DNA (ctDNA) and Pd (Ⅱ) meso-tetrakis(4-N-methyl pyridiniumyl) porphyrin (Pd-TMPyP) was investigated by steady solid-substrate room temperature phosphorescence (SS-RTP). The SS-RTP intensity and lifetime of Pd-TMPyP enhanced with the increasing ctDNA. The anion quenching experiment of Pd-TMPyP indicated that Pd-TMPyP intercalated into ctDNA, which was also approved by UV-Vis spectra.
2006, 17(2): 255-257
Abstract:
Thermoregulated organic biphasic system composed of triethylene glycol monomethyl ether (TGME) and n-heptane was first applied to the hydrogenation of 1-octene. Under the optimal conditions: P(H2)=5.0MPa, T=80℃, t=3h, 1-octene/Ru=1000(molar ratio), the yield of n-octane reached up to 99.6%. Furthermore, the simply decanted catalyst could be reused for 10 times without apparent loss of catalytic activity.
Thermoregulated organic biphasic system composed of triethylene glycol monomethyl ether (TGME) and n-heptane was first applied to the hydrogenation of 1-octene. Under the optimal conditions: P(H2)=5.0MPa, T=80℃, t=3h, 1-octene/Ru=1000(molar ratio), the yield of n-octane reached up to 99.6%. Furthermore, the simply decanted catalyst could be reused for 10 times without apparent loss of catalytic activity.
2006, 17(2): 258-260
Abstract:
Methyl methacrylate (MMA) was polymerized by using of benzoyl peroxide (BPO) and N, N-dimethylaniline (DMA) as an redox initiator in fluorous triphasic system at room temperature.The polymerization was occurred in both initiator layer and monomer layer in a U-tube. It was found that PMMA obtained from the initiator layer with relatively narrow polydispersity.(PDI=1.38)
Methyl methacrylate (MMA) was polymerized by using of benzoyl peroxide (BPO) and N, N-dimethylaniline (DMA) as an redox initiator in fluorous triphasic system at room temperature.The polymerization was occurred in both initiator layer and monomer layer in a U-tube. It was found that PMMA obtained from the initiator layer with relatively narrow polydispersity.(PDI=1.38)
2006, 17(2): 261-264
Abstract:
A novel efficient catalyst for the hydrogenation of carbon dioxide to formic acid ruthenium bisphosphine on functionalized silica was in situ synthesized, affording turnover frequency (TOF) of 1190 h-1 at 100% selectivity under 80C with total pressure of 16.0 MPa. The catalyst can be separated from the reaction mixture easily and reused with moderate loss of activity.
A novel efficient catalyst for the hydrogenation of carbon dioxide to formic acid ruthenium bisphosphine on functionalized silica was in situ synthesized, affording turnover frequency (TOF) of 1190 h-1 at 100% selectivity under 80C with total pressure of 16.0 MPa. The catalyst can be separated from the reaction mixture easily and reused with moderate loss of activity.
2006, 17(2): 265-268
Abstract:
A new stable salen Schiff base cobalt and crown ether sodium complex (SalCo-NaB18C6) was prepared through copolymerization. This copolymer complex was applied to catalytic oxidation of hydrocarbon compound with molecular oxygen without reductant, which was shown the higher activity and selectivity for ketone, and reused effectively.
A new stable salen Schiff base cobalt and crown ether sodium complex (SalCo-NaB18C6) was prepared through copolymerization. This copolymer complex was applied to catalytic oxidation of hydrocarbon compound with molecular oxygen without reductant, which was shown the higher activity and selectivity for ketone, and reused effectively.
2006, 17(2): 269-272
Abstract:
The induction of MT(metallothionein) by Cd(Ⅱ) and Zn(Ⅱ) in renal proximal tubule cells (LLC-PKI) and the effects of simultaneous administration of Cd(Ⅱ) and Zn(Ⅱ) on MT induction were discussed. The two metals administered together are able to induce MT to almost 40μg MT/mg protein. The additive production of MT may be due to two different effects by Cd(Ⅱ) and Zn(Ⅱ) on the activation of MT transcription. The experiments of simultaneous administration of Cd(Ⅱ) and Zn(Ⅱ) to the renal proximal tubule cells demonstrated the interaction of these metals, MT induction and proximal tubule toxicity.
The induction of MT(metallothionein) by Cd(Ⅱ) and Zn(Ⅱ) in renal proximal tubule cells (LLC-PKI) and the effects of simultaneous administration of Cd(Ⅱ) and Zn(Ⅱ) on MT induction were discussed. The two metals administered together are able to induce MT to almost 40μg MT/mg protein. The additive production of MT may be due to two different effects by Cd(Ⅱ) and Zn(Ⅱ) on the activation of MT transcription. The experiments of simultaneous administration of Cd(Ⅱ) and Zn(Ⅱ) to the renal proximal tubule cells demonstrated the interaction of these metals, MT induction and proximal tubule toxicity.
2006, 17(2): 273-276
Abstract:
Methoxy groups is favorable for film-forming property of oligophenylenevinylenes (OPVs) and the Langmuir-Blodgett film of 1, 4-bis (3, 4, 5-trimethoxystyryl)-2, 5-dimethoxybenzene (MOPV) was prepared. It might be the formation of H-aggregate of MOPV in the LB film that results in a 57 nm blue shift of λmax for the absorption and a 58 nm red shift of λmax for the fluorescence, respectively.
Methoxy groups is favorable for film-forming property of oligophenylenevinylenes (OPVs) and the Langmuir-Blodgett film of 1, 4-bis (3, 4, 5-trimethoxystyryl)-2, 5-dimethoxybenzene (MOPV) was prepared. It might be the formation of H-aggregate of MOPV in the LB film that results in a 57 nm blue shift of λmax for the absorption and a 58 nm red shift of λmax for the fluorescence, respectively.
2006, 17(2): 277-280
Abstract:
A new fixed carrier membrane material VSA-SA for CO2 separation was prepared through the chemical modification of PVSA. The selective permeation of CO2 through VSA-SA/PS composite membrane was performed with CO2/CH4 system. The VSA-SA/PS composite membranes possess better CO2 permselectivity than PVSA/PS composite membrane.
A new fixed carrier membrane material VSA-SA for CO2 separation was prepared through the chemical modification of PVSA. The selective permeation of CO2 through VSA-SA/PS composite membrane was performed with CO2/CH4 system. The VSA-SA/PS composite membranes possess better CO2 permselectivity than PVSA/PS composite membrane.
2006, 17(2): 281-284
Abstract:
The partial potential energy surface was constructed by ab initio method [QCISD(T)/6-311++G(2df, 2pd)]for F+CH4→HF+CH3 reaction system. It not only explained the reaction mechanism brought forward by Diego Troya by means of quasiclassical trajectory (QCT) but also successfully validated Kopin Liu's experimental phenomena about the existence of the reactive resonance. The lifetime of the scattering resonance state was about 0.07 ps. All these were in agreement with the experiments.
The partial potential energy surface was constructed by ab initio method [QCISD(T)/6-311++G(2df, 2pd)]for F+CH4→HF+CH3 reaction system. It not only explained the reaction mechanism brought forward by Diego Troya by means of quasiclassical trajectory (QCT) but also successfully validated Kopin Liu's experimental phenomena about the existence of the reactive resonance. The lifetime of the scattering resonance state was about 0.07 ps. All these were in agreement with the experiments.
