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2018 Volume 33 Issue 5
2018, 33(5): 1-4
doi: 10.3866/PKU.DXHX201712038
Abstract:
Classical chemistry is known for studying change and the results from the change. The interplay between chemistry and other disciplines, especially life science, strengthens the dynamic nature of chemistry. As a result, the concept of chemistry has changed. This article tries to provide a new understanding of modern chemistry.
Classical chemistry is known for studying change and the results from the change. The interplay between chemistry and other disciplines, especially life science, strengthens the dynamic nature of chemistry. As a result, the concept of chemistry has changed. This article tries to provide a new understanding of modern chemistry.
2018, 33(5): 5-9
doi: 10.3866/PKU.DXHX201801025
Abstract:
In view of the shortage of the traditional inorganic chemistry teaching, the WeChat platform was constructed. The establishment process and methods for the construction of the platform were introduced. The practical effect of the inorganic chemical WeChat platform on the teaching was analyzed, and the shortcomings in the traditional teaching can be made up. The positive role of WeChat platform in inorganic chemistry teaching was discussed, which improved the teachers' teaching level and students' learning ability, so that the goal of win-win for teachers and students was achieved.
In view of the shortage of the traditional inorganic chemistry teaching, the WeChat platform was constructed. The establishment process and methods for the construction of the platform were introduced. The practical effect of the inorganic chemical WeChat platform on the teaching was analyzed, and the shortcomings in the traditional teaching can be made up. The positive role of WeChat platform in inorganic chemistry teaching was discussed, which improved the teachers' teaching level and students' learning ability, so that the goal of win-win for teachers and students was achieved.
2018, 33(5): 10-17
doi: 10.3866/PKU.DXHX201712035
Abstract:
In the physical chemistry course, surface tension, surface free energy, and Young-Laplace equation are the basics in interface and colloidal chemistry. For students, it is the key to understand the above mentioned content for studying the follow-up knowledge. This paper presented the physical chemistry seminar via exploring the changes of two connected bubbles with different sizes. The demonstration experiments were valuable for students to know better surface tension, surface free energy, and Young-Laplace equation. Cultivating students' research abilities to apply knowledge and analyze problems were also based on discussing the similarities and differences between two connected balloon and two connected bubbles. The problem-based seminar on physical chemistry could be significant for the related courses.
In the physical chemistry course, surface tension, surface free energy, and Young-Laplace equation are the basics in interface and colloidal chemistry. For students, it is the key to understand the above mentioned content for studying the follow-up knowledge. This paper presented the physical chemistry seminar via exploring the changes of two connected bubbles with different sizes. The demonstration experiments were valuable for students to know better surface tension, surface free energy, and Young-Laplace equation. Cultivating students' research abilities to apply knowledge and analyze problems were also based on discussing the similarities and differences between two connected balloon and two connected bubbles. The problem-based seminar on physical chemistry could be significant for the related courses.
2018, 33(5): 18-23
doi: 10.3866/PKU.DXHX201711034
Abstract:
The curriculum construction is the foundation and starting point of the personnel training system. Aiming at training distinguished chemistry teachers, and with a view to provide references for the curriculum reform of chemistry education, we construct an undergraduate-master integrated curriculum system of chemistry education by the following approach:make clear the composition of the teaching ability of distinguished chemistry teacher to define the target of curriculum construction; construct the "integrated, two-level, three-dimension" curriculum system; adopt diversified measures and strategies to effectively promote the construction of the curriculum group.
The curriculum construction is the foundation and starting point of the personnel training system. Aiming at training distinguished chemistry teachers, and with a view to provide references for the curriculum reform of chemistry education, we construct an undergraduate-master integrated curriculum system of chemistry education by the following approach:make clear the composition of the teaching ability of distinguished chemistry teacher to define the target of curriculum construction; construct the "integrated, two-level, three-dimension" curriculum system; adopt diversified measures and strategies to effectively promote the construction of the curriculum group.
2018, 33(5): 24-28
doi: 10.3866/PKU.DXHX201712036
Abstract:
We herein proposed a system of quality assurance, feedback and continuous improvement for chemistry major based on outcome-based education (OBE) to update old knowledge and construct the new curriculum system. This communication systematically elaborates how to achieve quality assurance, feedback and continuous improvement of chemical major from major and curriculum quality, teaching quality, and the continuous improvements. This system strategically assures the continuous improvement of chemical major construction from our country requirements.
We herein proposed a system of quality assurance, feedback and continuous improvement for chemistry major based on outcome-based education (OBE) to update old knowledge and construct the new curriculum system. This communication systematically elaborates how to achieve quality assurance, feedback and continuous improvement of chemical major from major and curriculum quality, teaching quality, and the continuous improvements. This system strategically assures the continuous improvement of chemical major construction from our country requirements.
2018, 33(5): 29-32
doi: 10.3866/PKU.DXHX201801001
Abstract:
The main contents and the key point of implementation of "question-oriented" teaching method were briefly introduced. Some specifically utilized strategies for the inorganic chemistry laboratory course were put forward with preparation experiment of ammonium ferrous sulfate as an example.
The main contents and the key point of implementation of "question-oriented" teaching method were briefly introduced. Some specifically utilized strategies for the inorganic chemistry laboratory course were put forward with preparation experiment of ammonium ferrous sulfate as an example.
2018, 33(5): 33-37
doi: 10.3866/PKU.DXHX201712044
Abstract:
A number of experiments are involved into the use of gas in physical chemistry laboratory, and then design and installation of pipeline and vacuum systems are significant for many technicians. Here, taking the use of some typical gases in laboratory as examples we introduce our improvement on the pipeline and vacuum systems. This improvement brought the operability of these pipeline and vacuum systems, reduced the risk of gas leakage, and then enhanced the safety during experiments.
A number of experiments are involved into the use of gas in physical chemistry laboratory, and then design and installation of pipeline and vacuum systems are significant for many technicians. Here, taking the use of some typical gases in laboratory as examples we introduce our improvement on the pipeline and vacuum systems. This improvement brought the operability of these pipeline and vacuum systems, reduced the risk of gas leakage, and then enhanced the safety during experiments.
2018, 33(5): 38-43
doi: 10.3866/PKU.DXHX201712041
Abstract:
The hydrogen production from waste cooking oil by catalytic pyrolysis is transformed to the chemical reaction engineering experiment to replace the hydrogen production from carbon monoxide conversion in this study. The students start the experiment from raw materials to obtain the products by themselves. The experimental process can better help students understand the whole continuous chemical production process, stimulate students' interest in learning, improve the students' practical ability to engage in scientific research, reduce the experimental cost, and improve the safety of the experiment.
The hydrogen production from waste cooking oil by catalytic pyrolysis is transformed to the chemical reaction engineering experiment to replace the hydrogen production from carbon monoxide conversion in this study. The students start the experiment from raw materials to obtain the products by themselves. The experimental process can better help students understand the whole continuous chemical production process, stimulate students' interest in learning, improve the students' practical ability to engage in scientific research, reduce the experimental cost, and improve the safety of the experiment.
2018, 33(5): 44-50
doi: 10.3866/PKU.DXHX201801013
Abstract:
In order to promote and keep pace with the teaching of new nomenclature of organic compounds, some important revisions about teaching organic nomenclature suggested in Nomenclature of Organic Compounds 2017 were summarized. We proposed some concrete suggestions for using the new principles of the Nomenclature of Organic Compounds 2017 to name the complex organic compounds.
In order to promote and keep pace with the teaching of new nomenclature of organic compounds, some important revisions about teaching organic nomenclature suggested in Nomenclature of Organic Compounds 2017 were summarized. We proposed some concrete suggestions for using the new principles of the Nomenclature of Organic Compounds 2017 to name the complex organic compounds.
2018, 33(5): 51-55
doi: 10.3866/PKU.DXHX201801012
Abstract:
In this paper, we studied the physical meaning, measurement methods and potential problems of detection limit in analytical chemistry. The limitation of classical detection limit was also discussed. We studied the detection of thrombin by fluorescence quenching of Pt nanoparticles, based on the specific binding of thrombin aptamer to thrombin. We found a negative correlation between the measured signal and the logarithm of the concentration. In addition, the similar negative correlation was found in the determination of glucose by a glassy carbon electrode biosensor, based on CuGeO3 nanowires and glucose oxidase. The detection limit of the above two method conflicted with the classical detection limits. It appeared abnormal that the better the determination precision, the worse the detection limit.
In this paper, we studied the physical meaning, measurement methods and potential problems of detection limit in analytical chemistry. The limitation of classical detection limit was also discussed. We studied the detection of thrombin by fluorescence quenching of Pt nanoparticles, based on the specific binding of thrombin aptamer to thrombin. We found a negative correlation between the measured signal and the logarithm of the concentration. In addition, the similar negative correlation was found in the determination of glucose by a glassy carbon electrode biosensor, based on CuGeO3 nanowires and glucose oxidase. The detection limit of the above two method conflicted with the classical detection limits. It appeared abnormal that the better the determination precision, the worse the detection limit.
2018, 33(5): 56-60
doi: 10.3866/PKU.DXHX201801006
Abstract:
There are some vague concepts and improper divisions of extension of concepts in some textbooks of chemistry, which is attributed to the lack of logical knowledge. Some knowledge and rules on the concepts such as intension, extension, definition and division were introduced to help teachers to overcome the shortages.
There are some vague concepts and improper divisions of extension of concepts in some textbooks of chemistry, which is attributed to the lack of logical knowledge. Some knowledge and rules on the concepts such as intension, extension, definition and division were introduced to help teachers to overcome the shortages.
2018, 33(5): 61-65
doi: 10.3866/PKU.DXHX201801010
Abstract:
Gas-liquid equilibrium is important in classroom teaching and practical production. In this paper, the relationship and difference among Raoult's Law, Henry's Law, and azeotropic solution are discussed from the point of microscopic view. The different interactions between solvent-solvent, solvent-solute, and solute-solute lead to that the two laws are only useful for dilute solution. When the apparent vapor pressure of the solvent and solute are equal to each other by tuning their mole fraction, the azeotropic solution is produced.
Gas-liquid equilibrium is important in classroom teaching and practical production. In this paper, the relationship and difference among Raoult's Law, Henry's Law, and azeotropic solution are discussed from the point of microscopic view. The different interactions between solvent-solvent, solvent-solute, and solute-solute lead to that the two laws are only useful for dilute solution. When the apparent vapor pressure of the solvent and solute are equal to each other by tuning their mole fraction, the azeotropic solution is produced.
2018, 33(5): 66-71
doi: 10.3866/PKU.DXHX201801023
Abstract:
This paper introduces the basic principle and workflow of virtual screening of drugs in Schrödinger. In combination with the college bioinformatics and chemoinformatics course, it illustrates the principle and usage method of protein preparation, Lipinski's Rule of Five, ADME, Pan-assay Interference Compounds (PAINS), high throughput virtual screening, standard precision screening, extra precision screening and score ranking of MM/GBSA. The Schrödinger can be demonstrated to improve students' understanding of protein structure, molecular conformation, virtual drug screening and computer-aided molecular design in the college bioinformatics and chemoinformatics teaching. Due to the friendly graphical interface, Schrödinger can give students the intuitive experience and enrich the college course. In addition, Schrödinger has a good application value in the drug design field. It can reduce the cost of drug screening and improve the efficiency of drug discovery.
This paper introduces the basic principle and workflow of virtual screening of drugs in Schrödinger. In combination with the college bioinformatics and chemoinformatics course, it illustrates the principle and usage method of protein preparation, Lipinski's Rule of Five, ADME, Pan-assay Interference Compounds (PAINS), high throughput virtual screening, standard precision screening, extra precision screening and score ranking of MM/GBSA. The Schrödinger can be demonstrated to improve students' understanding of protein structure, molecular conformation, virtual drug screening and computer-aided molecular design in the college bioinformatics and chemoinformatics teaching. Due to the friendly graphical interface, Schrödinger can give students the intuitive experience and enrich the college course. In addition, Schrödinger has a good application value in the drug design field. It can reduce the cost of drug screening and improve the efficiency of drug discovery.
2018, 33(5): 72-82
doi: 10.3866/PKU.DXHX201710013
Abstract:
Graphene, an emerging inorganic material, has attracted wide attention from scientific and industrial communities. This review provides a brief view of graphene's emergence, structural characteristics and physical properties as well as several applications in both scientific research and life. Finally, the challenges of graphene are summarized.
Graphene, an emerging inorganic material, has attracted wide attention from scientific and industrial communities. This review provides a brief view of graphene's emergence, structural characteristics and physical properties as well as several applications in both scientific research and life. Finally, the challenges of graphene are summarized.
2018, 33(5): 83-92
doi: 10.3866/PKU.DXHX2018020102
Abstract:
