【无机化学学报】doi: 10.11862/CJIC.20240153
A novel compound (H2L)SCN (5-methyl-3-phenyl-2H-pyrazol-1-ium thiocyanate) has been obtained by the reaction of thiosemicarbazide with benzoylacetone in ethanol. Two zinc(Ⅱ) complexes [Zn(HL)2(NCS)(CH3COO)] (1) and [Zn2(L)2(HL)2(NCS)2]2·2CH3OH (2) have been synthesized by the coordination reactions of Zn(OAc)2·2H2O or ZnCl2 with (H2L)SCN under reflux conditions. Elemental analyses and single-crystal X-ray diffraction have confirmed the structures of the synthesized compounds. The (H2L)SCN ligand and complex 1 pertain to the triclinic system with space group P1, while complex 2 belongs to the monoclinic system with space group P21/n. Additionally, the antibacterial activities of the compounds were evaluated in vitro using the agar diffusion method against the bacterial strains (Candida albicans, Staphylococcus aureus, and Escherichia coli). The results showed that the ligand exhibited relatively good antibacterial activities against the bacteria, and the complexes possessed stronger antibacterial activities against the same bacteria than the free ligand.
