二维材料“遇见”生物大分子：机遇与挑战

引用本文: 杜春保, 胡小玲, 张刚, 程渊. 二维材料“遇见”生物大分子：机遇与挑战[J]. 物理化学学报, 2019, 35(10): 1078-1089. doi: 10.3866/PKU.WHXB201812057 shu

Citation: DU Chunbao, HU Xiaoling, ZHANG Gang, CHENG Yuan. 2D Materials Meet Biomacromolecules: Opportunities and Challenges[J]. Acta Physico-Chimica Sinica, 2019, 35(10): 1078-1089. doi: 10.3866/PKU.WHXB201812057 shu

二维材料“遇见”生物大分子：机遇与挑战

杜春保 ^{1,
,} ,
胡小玲 ^2, ,
张刚 ^3, ,
程渊 ^{3,
,}

1.
西安石油大学化学化工学院，西安 710065
2.
西北工业大学理学院，西安 710072
3.
新加坡科技研究局高性能计算研究所，新加坡 138632

作者简介: 杜春保，1988年生。2017年在西北工业大学获得博士学位。现就职于西安石油大学。主要研究方向为纳米材料生物效应、功能高分子材料与多孔材料催化。;

程渊，1981生。2003年在复旦大学获得学士学位；2008年在新加坡国立大学获得博士学位。现任新加坡科技研究局高性能计算研究所科学家。主要研究方向为纳米材料跨尺度模拟、仿生材料力学行为与应用。;

通讯作者: 杜春保, duchunbao218@126.com; 程渊, chengy@ihpc.a-star.edu.sg

基金项目:
国家自然科学基金(51433008)和高级制造与工程(A1898b0043)资助项目

摘要: 二维材料的超薄原子层结构使其具有独特的力学性能、导热导电性以及巨大的比表面积，在能源存储、催化、传感和生物医学等领域引起了国内外学者的广泛关注。将二维材料与具有生物活性的生物大分子相结合可以为开发具有优异电学、力学和生物学功能的特种功能材料提供新的方法和途径。近年来，科研工作者针对这一方向展开了广泛的研究，取得了一系列重要的成果，使二维材料与生物大分子的结合与应用成为了新的研究热点。本文综述了近年来二维材料和生物大分子之间的相互作用及应用的研究进展，重点介绍了二维材料与生物大分子在分子水平上的相互作用机理，还总结了基于二维材料与生物大分子之间的相互作用在工程、疾病治疗和抗菌中的应用，并对其未来的研究趋势提出了展望。

关键词:

English

2D Materials Meet Biomacromolecules: Opportunities and Challenges

DU Chunbao ^{1,
,} ,
HU Xiaoling ^2, ,
ZHANG Gang ^3, ,
CHENG Yuan ^{3,
,}

1.
College of Chemistry and Chemical Engineering, Xi'an Shiyou University, Xi'an 710065, P. R. China
2.
School of Natural and Applied Sciences, Northwestern Polytechnical University, Xi'an 710072, P. R. China
3.
Institute of High Performance Computing, A*STAR, 138632, Singapore

Corresponding author: Emails: duchunbao218@126.com (D.C.); Emails: chengy@ihpc.a-star.edu.sg (C.Y.)

Received Date: 31 December 2018
Accepted Date: 24 January 2019
Revised Date: 23 January 2019
Available Online: 15 October 2019
Fund Project:
The project was supported by the National Natural Science Foundation of China (51433008) and the RIE2020 Advanced Manufacturing and Engineering (AME) Programmatic grant, Work Package 4(A1898b0043)

Abstract: With the rapid development of science and technology, various nanomaterials have continually emerged to meet human needs. As a newly emerging class of nanomaterials, two-dimensional (2D) materials have received wide attention recently in energy storage, catalysis, sensing and biomedicine due to their unique features such as good mechanical property, high specific surface area, excellent thermal and electrical conductivity. Biomacromolecules are the special organic molecules with various biological activities which exist extensively in every aspect of human life. When 2D materials meet biomacromolecules to display their own unique advantages, more opportunities and challenges have arisen for the exploitation and fabrication of novel nanomaterials with unique electrical, mechanical, biological properties and specific functions. In recent years, extensive research has been carried out with outstanding achievement thus the combination of 2D materials and biomacromolecules becomes a new hotspot. There were generally two binding interactions between 2D materials and biomacromolecules, namely non-covalent binding (electrostatic interaction, hydrophobic effect, π–π stacking, van der Waals interaction) and covalent binding (special chemical reactions between the functional groups of 2D materials and biomacromolecules). In addition, due to the excellent photothermal conversion performance, 2D materials could exhibit a non-contact interaction to biomacromolecules through the photo-thermal effect which has greatly broadened their applications. Up to now, numerous studies have clearly revealed the binding and effect mechanism and the research will be more focused on expanding the scope and application. Currently, the combination of 2D materials and biomacromolecules has widely involved in many cutting-edge applications such as flexible device, biosensor, smart skin, drug delivery, antibacterial, disease therapy and so on. Although a lot of progress has been made, several highlight open questions still need to be urgently addressed, such as the production cost of 2D materials, biological activity of biomacromolecules, stability and biocompatibility of 2D/biomacromolecule nanomaterials. This review summarizes the interactions between some typical 2D materials (i.e. graphene, graphene oxide, nitrogen-doped graphene, molybdenum disulfide, phosphorene, silylene and germanene) and biomacromolecules (i.e. silk protein, lysozyme, bovine serum albumin, bovine hemoglobin, ovalbumin, villin, bovine fibrinogen, DNA/RNA, glucose oxidase and chitosan) and focuses on the recent progress of some typical applications (i.e. engineering application, disease therapy and antibacterial). The non-covalent and covalent bindings of 2D materials and biomacromolecules are discussed in detail, and the applications of the combination of 2D materials and biomacromolecules in engineering and bioscience have been reviewed. Finally, the challenges for the future development of 2D materials and biomacromolecules are also briefly proposed.

Key words:

1. [1]
  Zhang, Z.; Chen, P.; Duan, X.; Zang, K.; Luo, J.; Duan, X. Science 2017, 357, 788. doi: 10.1126/science.aan6814
2. [2]
  Lang, H.; Zhang, S.; Liu, Z. Phys. Rev. B 2016, 94, 235306. doi: 10.1103/PhysRevB.94.235306
3. [3]
  Zhang, G.; Zhang, Y. W. Chin. Phys. B 2017, 26, 034401. doi: 10.1088/1674-1056/26/3/034401
4. [4]
  Zhang, G.; Zhang, Y W. J. Mater. Chem. C 2017, 5, 7684. doi: 10.1039/c7tc01088e
5. [5]
  Zhang, G.; Zhang, Y. W. Mech. Mater. 2015, 91, 382. doi: 10.1016/j.mechmat.2015.03.009
6. [6]
  Xie, G.; Ju, Z.; Zhou, K.; Wei, X.; Guo, Z.; Cai, Y.; Zhang, G. NPJ Comput. Mater. 2018, 4, 21. doi: 10.1038/s41524-018-0076-9
7. [7]
  刘强, 王晓珊, 王加亮, 黄晓.物理化学学报, 2019, 35, 1099. doi: 10.3866/PKU.WHXB201811005Liu, Q.; Wang, X.; Wang, J.; Huang, X. Acta Phys.-Chim. Sin. 2019, 35, 1099. doi: 10.3866/PKU.WHXB201811005
8. [8]
  Ouyang, F.; Peng, S.; Yang, Z.; Chen, Y.; Zou, H.; Xiong, X. Phys. Chem. Chem. Phys. 2014, 16, 20524. doi: 10.1039/C4CP02090A
9. [9]
  Zhang, S.; Wang, J.; Li, Z.; Zhao, R.; Tong, L.; Liu, Z.; Zhang, J.; Liu, Z. J. Phys. Chem. C 2016, 120, 10605. doi: 10.1021/acs.jpcc.5b12388
10. [10]
  Zhou, L.; Liao, L.; Wang, J.; Yu, J.; Li, D.; Xie, Q.; Liu, Z.; Yang, Y.; Guo, X.; Liu, Z. Adv. Mater. 2016, 28, 2148. doi: 10.1002/adma.201670070
11. [11]
  Li, Z.; Liu, Z.; Liu, Z. Nano Res. 2017, 10, 2005. doi: 10.1007/s12274-016-1388-z
12. [12]
  刘南舒, 周思, 赵纪军.物理化学学报, 2019, 35, 1142. doi: 10.3866/PKU.WHXB201810040Liu, N.; Zhou, S.; Zhao, J. Acta Phys.-Chim. Sin. 2019, 35, 1142. doi: 10.3866/PKU.WHXB201810040
13. [13]
  王可心, 史刘嵘, 王铭展, 杨皓, 刘忠范, 彭海琳.物理化学学报, 2019, 35, 1112. doi: 10.3866/PKU.WHXB201805032Wang, K.; Shi, L.; Wang, M.; Yang, H.; Liu, Z.; Peng, H. Acta Phys.-Chim. Sin. 2019, 35, 1112. doi: 10.3866/PKU.WHXB201805032
14. [14]
  Qin, G.; Du, A.; Sun, Q. Energy Technol.-Ger 2018, 6, 205. doi: 10.1002/ente.201700413
15. [15]
  Zhao, R.; Li, F.; Liu, Z.; Liu, Z.; Ding, F. Phys. Chem. Chem. Phys. 2015, 17, 29327. doi: 10.1039/c5cp04833h
16. [16]
  Zhao, R.; Zhao, X.; Liu, Z.; Ding, F.; Liu, Z. Nanoscale 2017, 9, 3561. doi: 10.1039/c6nr09368j
17. [17]
  Wei, X.; Wang, Y.; Shen, Y.; Xie, G.; Xiao, H.; Zhong, J.; Zhang, G. Appl. Phys. Lett. 2014, 105, 103902. doi: 10.1063/1.4895344
18. [18]
  Li, W.; Zhang, G.; Guo, M.; Zhang, Y. W. Nano Res. 2014, 7, 518. doi: 10.1007/s12274-014-0418-y
19. [19]
  Ouyang, F.; Yang, Z.; Ni, X.; Wu, N.; Chen, Y.; Xiong, X. Appl. Phys. Lett. 2014, 104, 071901. doi: 10.1063/1.4865902
20. [20]
  Li, W.; Guo, M.; Zhang, G.; Zhang, Y. W. Phys. Rev. B 2014, 89, 205402. doi: 10.1103/PhysRevB.89.205402
21. [21]
  Li, W.; Yang, Y.; Weber, J.; Zhang, G.; Zhou, R. ACS Nano 2016, 10, 1829. doi: 10.1021/acsnano.5b05250
22. [22]
  Zhu, P.; Chen, Y.; Zhou, Y.; Yang, Z.; Wu, D.; Xiong, X.; Ouyang, F. Int. J. Hydrogen. 2018, 43, 14087. doi: 10.1016/j.ijhydene.2018.05.175
23. [23]
  刘新科, 王佳乐, 许楚瑜, 罗江流, 梁迪斯, 岑俞诺, 吕有明, 李治文.物理化学学报, 2019, 35, 1134. doi: 10.3866/PKU.WHXB201809013Liu, X.; Wang, J.; Xu, C.; Luo, J.; Liang, D.; Cen, Y.; Lü, Y.; Li, Z. Acta Phys.-Chim. Sin. 2019, 35, 1134. doi: 10.3866/PKU.WHXB201809013
24. [24]
  Zhu, Z.; Cheng, Y.; Schwingenschögl, U. Phys. Rev. Lett. 2013, 110, 077202. doi: 10.1103/PhysRevLett.110.077202
25. [25]
  Jing, Y.; Zhou, Z.; Cabrera, C. R. C.; Chen, Z. J. Phys. Chem. C 2013, 117, 25409. doi: 10.1021/jp410969u
26. [26]
  Gan, L. Y.; Zhang, L. H.; Zhang, Q.; Guo, C. S.; Schwingenschögl, U.; Zhao, Y. Phys. Chem. Chem. Phys. 2016, 18, 3080. doi: 10.1039/c5cp05695k
27. [27]
  Zhang, M.; Zhu, Y.; Wang, X.; Feng, Q.; Qiao, S.; Wen, W.; Chen, Y.; Cui, M.; Zhang, J.; Cai, C.; et al. J. Am. Chem. Soc. 2015, 137, 7051. doi: 10.1021/jacs.5b03807
28. [28]
  Rivera, P.; Schaibley, J. R.; Jones, A. M.; Ross, J. S.; Wu, S.; Aivazian, G.; Klement, P.; Seyler, K.; Clark, G.; Ghimire, N. J.; et al. Nat. Commun. 2015, 6, 6242. doi: 10.1038/ncomms7242
29. [29]
  Huang, C.; Wu, S.; Sanchez, A. M.; Peters, J. J. P.; Beanland, R.; Ross, J. S.; Rivera, P.; Yao, W.; Cobden, D. H.; Xu, X. Nat. Mater. 2013, 13, 1096. doi: 10.1038/nmat4064
30. [30]
  Xi, X.; Zhao, L.; Wang, Z.; Berger, H.; Forró, L.; Shan, J.; Mak, K. F. Nat. Nanotechnol. 2015, 10, 765. doi: 10.1038/nnano.2015.143
31. [31]
  Checkelsky, J. G.; Hor, Y. S.; Cava, R. J.; Ong, N. P. Phys. Rev. Lett. 2011, 106, 196801. doi: 10.1103/PhysRevLett.106.196801
32. [32]
  Zhou, L.; Xu, K.; Zubair, A.; Liao, A. D.; Fang, W.; Ouyang, F.; Lee, Y. H.; Ueno, K.; Saito, R.; Palacios, T.; et al. J. Am. Chem. Soc. 2015, 137, 11892. doi: 10.1021/jacs.5b07452
33. [33]
  Zhou, L.; Zubair, A.; Wang, Z.; Zhang, X.; Ouyang, F.; Fang, W.; Ueno, K.; Li, J.; Palacios, T.; Kong, J.; Dresselhaus, M. S. Adv. Mater. 2016, 28, 9526. doi: 10.1002/adma.201602687
34. [34]
  Zhou, L.; Xu, K.; Zubair, A.; Zhang, X.; Ouyang, F.; Palacios, T.; Dresselhaus, M.; Li, Y.; Kong, J. Adv. Funct. Mater. 2017, 27, 1603491. doi: 10.1002/adfm.201603491
35. [35]
  Ha, Y. E.; Jo, M. Y.; Park, J.; Kang, Y. C.; Yoo, S. I.; Kim, J. H.J. Phys. Chem. C 2013, 117, 2646. doi: 10.1021/jp311148d
36. [36]
  Wu, D.; Zheng, X.; Chen, X.; Xie, Q.; Shi, J.; Huang, Y.; Zhang, X.; Ouyang, F.; Y. Gao, ; Huang, H. J. Phys. Chem. C 2018, 122, 1860. doi: 10.1021/acs.jpcc.7b10666
37. [37]
  Zhou, P.; Xu, Q.; Li, H.; Wang, Y.; Yan, B.; Zhou, Y.; Chen, J.; Zhang, J.; Wang, K. Angew. Chem. Int. Ed. Engl. 2015, 54, 15226. doi: 10.1002/anie.201508216
38. [38]
  Li, S. L.; Yin, H.; Kan, X.; Gan, L. Y.; Schwingenschögl, U.; Zhao, Y. Phys. Chem. Chem. Phys. 2017, 19, 30069. doi: 10.1039/c7cp05195f
39. [39]
  Li, W.; Yang, Y.; Zhang, G.; Zhang, Y. W. Nano Lett. 2015, 15, 1691. doi: 10.1021/nl504336h
40. [40]
  Cai, Y.; Ke, Q.; Zhang, G.; Yakobson, B. I.; Zhang, Y. W. J. Am. Chem. Soc. 2016, 138, 10199. doi: 10.1021/jacs.6b04926
41. [41]
  Shi, R.; Dai, X.; Li, W.; Lu, F.; Liu, Y.; Qu, H.; Li, H.; Chen, Q.; Tian, H.; Wu, E. ACS Nano 2017, 11, 9500. doi: 10.1021/acsnano.7b05328
42. [42]
  Zhang, S.; Mao, N.; Wu, J.; Tong, L.; Zhang, J.; Liu, Z. Small 2017, 13, 1700466. doi: 10.1002/smll.201700466
43. [43]
  Cheng, Y.; Zhang, G.; Zhang, Y.; Chang, T.; Pei, Q. X.; Cai, Y.; Zhang, Y. W. Nanoscale 2018, 10, 1660. doi: 10.1039/c7nr07226k
44. [44]
  Hu, M.; Yang, Z.; Zhou, W.; Li, A.; Pan, J.; Ouyang, F. Phys. E 2018, 98, 60. doi: 10.1016/j.physe.2017.12.027
45. [45]
  刘忠范.物理化学学报, 2016, 32, 1053. doi: 10.3866/PKU.WHXB201603302Liu, Z. Acta Phys.-Chim. Sin. 2016, 32, 1053. doi: 10.3866/PKU.WHXB201603302
46. [46]
  尹海峰, 向功周, 岳莉, 张红.物理化学学报, 2015, 31, 67. doi: 10.3866/PKU.WHXB201411211Yin, H.; Xiang, G.; Yue, L.; Zhang, H. Acta Phys.-Chim. Sin. 2015, 31, 67. doi: 10.3866/PKU.WHXB201411211
47. [47]
  Li, L.; Lu, S. Z.; Pan, J.; Qin, Z.; Wang, Y. Q.; Wang, Y.; Cao, G. Y.; Du, S.; Gao, H. J. Adv. Mater. 2014, 26, 4820.doi: 10.1002/adma.201400909
48. [48]
  Chen, J.; Ge, Y.; Zhou, W.; Peng, M.; Pan, J.; Ouyang, F. J. Phys.-Condens. Mat. 2018, 30, 245701. doi: 10.1088/1361-648x/aac186
49. [49]
  Chen, J.; Yang, Z.; Zhou, W.; Zou, H.; Li, M.; Ouyang, F. Phys. Status. Solidi.-R. 2018, 12, 1800038. doi: 10.1002/pssr.201800038
50. [50]
  吴昊, 严仲.物理化学学报, 2019, 35, 1052. doi: 10.3866/PKU.WHXB201801262Wu, H.; Yan, Z. Acta Phys.-Chim. Sin. 2019, 35, 1052. doi: 10.3866/PKU.WHXB201801262
51. [51]
  奚晋扬, 中村悠马, 赵天琦, 王冬, 帅志刚.物理化学学报, 2018, 34, 961. doi: 10.3866/PKU.WHXB201802051Xi, J.; Nakamura, Y.; Zhao, T.; Wang, D.; Shuai, Z. Acta Phys.-Chim. Sin. 2018, 34, 961. doi: 10.3866/PKU.WHXB201802051
52. [52]
  Shi, L.; Yao, D.; Zhang, G.; Li, B. Appl. Phys. Lett. 2010, 96, 173108. doi: 10.1063/1.3421543
53. [53]
  Chen, D.; Pei, Q. Chem. Rev. 2017, 117, 11239. doi: 10.1021/acs.chemrev.7b00019
54. [54]
  Chhowalla, M.; Liu, Z.; Zhang, H. Chem. Soc. Rev. 2015, 44, 2584. doi: 10.1039/c5cs90037a
55. [55]
  Chen, P.; Zhang, Z.; Duan, X.; Duan, X. Chem. Soc. Rev. 2018, 47, 3129. doi: 10.1039/C7CS00887B
56. [56]
  Xie, G.; Ding, D.; Zhang, G. Adv. Phys. X 2018, 3, 1480417. doi: 10.1080/23746149.2018.1480417
57. [57]
  Du, C.; Hu, X.; Guan, P.; Guo, L.; Qian, L.; Li, J.; Song, R.; Tang, Y. J. Mater. Sci. 2015, 50, 427. doi: 10.1007/s10853-014-8602-8
58. [58]
  Du, C.; Hu, X.; Guan, P.; Guo, L.; Qian, L.; Song, R.; Li, J.; Wang, C. J. Mater. Chem. B 2015, 3, 3044. doi: 10.1039/c4tb02030h
59. [59]
  Du, C.; Hu, X.; Guan, P.; Gao, X.; Song, R.; Li, J.; Qian, L.; Zhang, N.; Guo, L. J. Mater. Chem. B 2016, 4, 1510. doi: 10.1039/c5tb02633d
60. [60]
  Du, C.; Zhang, N.; Ding, S.; Gao, X.; Guan, P.; Hu, X. Polym. Chem. 2016, 7, 4531. doi: 10.1039/c6py00747c
61. [61]
  Du, C.; Hu, X.; Cheng, Y.; Gao, J.; Zhang, Y. W.; Su, K.; Li, Z.; Zhang, N.; Chang, N.; Zeng, K. Mat. Sci. Eng. C 2018, 83, 169. doi: 10.1016/j.msec.2017.10.002
62. [62]
  Zhang, N.; Hu, X.; Guan, P.; Du, C.; Li, J.; Qian, L.; Zhang, X.; Ding, S.; Li, B. Chem. Eng. J. 2017, 317, 356. doi: 10.1016/j.cej.2017.02.066
63. [63]
  Cheng, Y.; Koh, L. D.; Li, D.; Ji, B.; Zhang, Y.; Yeo, J.; Guan, G.; Han, M. Y.; Zhang, Y. W. ACS Appl. Mater. Interfaces 2015, 7, 21787. doi: 10.1021/acsami.5b05615
64. [64]
  Cheng, Y.; Koh, L. D.; Li, D.; Ji, B.; Han, M. Y.; Zhang, Y. W. J. R. Soc. Interface 2014, 11, 20140305. doi: 10.1098/rsif.2014.0305
65. [65]
  Xu, C.; Li, D.; Cheng, Y.; ·Liu, M.; Zhang, Y. W.·Ji, B. Acta Mech. Sin. 2015, 31, 416. doi: 10.1007/s10409-015-0404-y
66. [66]
  Wang, F.; Aravind, S. S. J.; Wu, H.; Forys, J.; Venkataraman, V.; Ramanujachary, K.; Hu, X. Mat. Sci. Eng. C 2017, 79, 728. doi: 10.1016/j.msec.2017.05.120
67. [67]
  Zhang, N.; Hu, X.; Guan, P.; Zeng, K.; Cheng, Y. J. Phys. Chem. C 2019, 123, 897. doi: 10.1021/acs.jpcc.8b09893
68. [68]
  Zuo, G.; Zhou, X.; Huang, Q.; Fang, H.; Zhou, R. J. Phys. Chem. C 2011, 115, 23323. doi: 10.1021/jp208967t
69. [69]
  Chong, Y.; Ge, C.; Yang, Z.; Garate, J. A.; Gu, Z.; Weber, J. K.; Liu, J.; Zhou, R. ACS Nano 2015, 9, 5713. doi: 10.1021/nn5066606
70. [70]
  Tu, Y.; Lv, M.; Xiu, P.; Huynh, T.; Huang, Q.; Fan, C.; Zhang, M.; Fang, H.; Zhou, R. Nat. Nanotechnol. 2013, 8, 594. doi: 10.1038/NNANO.2013.125
71. [71]
  Wang, Q., Zhai, X., Crowe, M., Gou, L., Li, Y., Li, D., Zhang, L., Diao, J., Ji, B. Sci. China Phys. Mech. 2019, 62, 64611. doi: 10.1007/s11433-018-9317-7
72. [72]
  Li, B.; Li, W.; Perez-Aguilar, J. M.; Zhou, R. Small 2017, 13, 1603685. doi: 10.1002/smll.201603685
73. [73]
  Gu, Z.; Zhao, L.; Liu, S.; Duan, G.; Perez-Aguilar, J. M.; Luo, J.; Li, W.; Zhou, R. ACS Nano 2017, 11, 3198. doi: 10.1021/acsnano.7b00236
74. [74]
  Gu, Z.; Li, W.; Hong, L.; Zhou, R. J. Chem. Phys. 2016, 144, 175103. doi: 10.1063/1.4948459
75. [75]
  Li, W.; Guo, M.; Zhang, G.; Zhang, Y. W. Chem. Mater. 2014, 26, 5625. doi: 10.1021/cm5021756
76. [76]
  Liu, Y.; Wu, H.; Cheng, H. C.; Yang, S.; Zhu, E.; He, Q.; Ding, M.; Li, D.; Guo, J.; Weiss, N.; et al. Nano Lett. 2015, 15, 3030. doi: 10.1021/nl504957p
77. [77]
  Liu, X.; Gao, J.; Zhang, G.; Zhang, Y. W. Nano Res. 2017, 10, 2944. doi: 10.1007/s12274-017-1504-8
78. [78]
  Yang, Z.; Pan, J.; Liu, Q.; Wu, N.; Hu, M.; Ouyang, F. Phys. Chem. Chem. Phys. 2017, 19, 1303. doi: 10.1039/c6cp07327a
79. [79]
  Wang, X.; Li, B.; Bell, D. R.; Li, W.; Zhou, R. J. Mater. Chem. A 2017, 5, 23020. doi: 10.1039/C7TA05995G
80. [80]
  Liang, J.; Zhang, J.; Li, Z.; Hong, H.; Wang, J.; Zhang, Z.; Zhou, X.; Qiao, R.; Xu, J.; Gao, P.; et al. Nano Lett. 2017, 17, 7539. doi: 10.1021/acs.nanolett.7b03476
81. [81]
  Guan, G.; Liu, S.; Cheng, Y.; Zhang, Y. W.; Han, M. Y. Nanoscale 2018, 10, 10911. doi: 10.1039/c8nr02121j
82. [82]
  Zhang, W.; Huynh, T.; Xiu, P.; Zhou, B.; Ye, C.; Luan, B.; Zhou, R. Carbon 2015, 94, 895. doi: 10.1016/j.carbon.2015.07.075
83. [83]
  Hussain, T.; Vovusha, H.; Kaewmaraya, T.; Amornkitbamrung, V.; Ahuja, R. Sens. Actuators B: Chem. 2018, 255, 2713. doi: 10.1016/j.snb.2017.09.083
84. [84]
  Jagvaral, Y.; He, H.; Pandey, R. 2D Mater. 2018, 5, 015012. doi: 10.1088/2053-1583/aa8c92
85. [85]
  Shen, J.; Shi, M.; Yan, B.; Ma, H.; Li, N.; Hu, Y.; Ye, M. Colloids Surf. B 2010, 81, 434. doi: 10.1016/j.colsurfb.2010.07.035
86. [86]
  Li, H.; Fierens, K.; Zhang, Z.; Vanparijs, N.; Schuijs, M. J.; Steendam, K. V.; Gracia N. F.; Rycke, R. D.; Beer, T. D.; Beuckelaer, A. D.; et al. ACS Appl. Mater. Interfaces 2016, 8, 1147. doi: 10.1021/acsami.5b08963
87. [87]
  Hong, S. G.; Kim, J. H.; Kim, R. E.; Kwon, S. J.; Kim, D. W.; Jung, H. T.; Dordick, J. S.; Kim, J. Biotechnol. Bioproc. E 2016, 21, 573. doi: 10.1007/s12257-016-0373-4
88. [88]
  Wang, Z.; Ge, Z.; Zheng, X.; Chen, N.; Peng, C.; Fan, C.; Huang, Q. Nanoscale 2012, 4, 394. doi: 10.1039/c1nr11174d
89. [89]
  Yang, Q.; Pan, X.; Clarke, K.; Li, K. Ind. Eng. Chem. Res. 2012, 51, 310. doi: 10.1021/ie201391e
90. [90]
  Liu, Y.; Tao, L. Q.; Wang, D. Y.; Zhang, T. Y.; Yang, Y.; Ren, T. L. Appl. Phys. Lett. 2017, 110, 123508. doi: 10.1063/1.4978374
91. [91]
  Zeng, Q.; Cheng, J.; Tang, L.; Liu, X.; Liu, Y.; Li, J.; Jiang, J. Adv. Funct. Mater. 2010, 20, 3366. doi: 10.1002/adfm.201000540
92. [92]
  Guo, C. X.; Zheng, X. T.; Lu, Z. S.; Lou, X. W.; Li, C. M. Adv. Mater. 2010, 22, 5164. doi: 10.1002/adma.201001699
93. [93]
  Al-Dirini, F.; Mohammed, M. A.; Hossain, M. S.; Hossain, F. M.; Nirmalathas, A.; Skafidas, E. Nanoscale 2016, 8, 10066. doi: 10.1039/c5nr05274b
94. [94]
  Zhang, X.; Wang, L.; Lu, Q.; Kaplan, D. L. ACS Appl. Mater. Interfaces 2018, 10, 22924. doi: 10.1021/acsami.8b04777
95. [95]
  Yang, Z.; Ge, C.; Liu, J.; Chong, Y.; Gu, Z.; Jimenez-Cruz, C. A.; Chai, Z.; Zhou, R. Nanoscale 2015, 7, 18725. doi: 10.1039/c5nr01172h
96. [96]
  Cheng, Y.; Koh, L. D.; Wang, F.; Li, D.; Ji, B.; Yeo, J.; Guan, G.; Han, M. Y.; Zhang, Y. W. Nanoscale 2017, 9, 9181. doi: 10.1039/c7nr01428g
97. [97]
  Weng, Q.; Wang, B.; Wang, X.; Hanagata, N.; Li, X.; Liu, D.; Wang, X.; Jiang, X.; Bando, Y.; Golberg, D. ACS Nano 2014, 8, 6123. doi: 10.1021/nn5014808
98. [98]
  Chu, J.; Shi, P.; Yan, W.; Fu, J.; Yang, Z.; He, C.; Deng, X.; Liu, H. Nanoscale 2018, 10, 9547. doi: 10.1039/c8nr02538j
99. [99]
  Yin, W.; Yan, L.; Yu, J.; Tian, G.; Zhou, L.; Zheng, X.; Zhang, X.; Yong, Y.; Li, J.; Gu, Z.; et al. ACS Nano 2014, 8, 6922. doi: 10.1021/nn501647j
100. [100]
  Yong, Y.; Zhou, L.; Gu, Z.; Yan, L.; Tian, G.; Zheng, X.; Liu, X.; Zhang, X.; Shi, J.; Cong, W.; et al. Nanoscale 2014, 6, 10394. doi: 10.1039/c4nr02453b
101. [101]
  Shao, J.; Xie, H.; Wang, H.; Zhou, W.; Luo, Q.; Yu, X. F.; Chu, P. K. ACS Appl. Mater. Interfaces 2018, 10, 1155. doi: 10.1021/acsami.7b17117
102. [102]
  Yang, X.; Wang, D.; Shi, Y.; Zou, J.; Zhao, Q.; Zhang, Q.; Huang, W.; Shao, J.; Xie, X.; Dong, X. ACS Appl. Mater. Interfaces 2018, 10, 12431. doi: 10.1021/acsami.8b00276
103. [103]
  Tao, W.; Ji, X.; Xu, X.; Islam, M. A.; Li, Z.; Chen, S.; Saw, P. E.; Zhang, H.; Bharwani, Z.; Guo, Z.; et al. Angew. Chem. Int. Ed. 2017, 56, 11896. doi: 10.1002/anie.201703657
104. [104]
  Wang, K.; Chen, Q.; Xue, W.; Li, S.; Liu, Z. ACS Biomater. Sci. Eng. 2017, 3, 2325. doi: 10.1021/acsbiomaterials.7b00499
105. [105]
  Zhang, A.; Li, A.; Tian, W.; Li, Z.; Wei, C.; Sun, Y.; Zhao, W.; Liu, M.; Liu, J. Chem. Eur. J. 2017, 23, 11346. doi: 10.1002/chem.201701916
106. [106]
  Lin, L. S.; Yang, X.; Niu, G.; Song, J.; Yang, H. H.; Chen, X. Nanoscale 2016, 8, 2116. doi: 10.1039/c5nr07552a
107. [107]
  Feng, W.; Chen, L.; Qin, M.; Zhou, X.; Zhang, Q.; Miao, Y.; Qiu, K.; Zhang, Y.; Hea, C. Sci. Rep. 2015, 5, 17422. doi: 10.1038/srep17422
108. [108]
  Sun, Z.; Xie, H.; Tang, S.; Yu, X. F.; Guo, Z.; Shao, J.; Zhang, H.; Huang, H.; Wang, H.; Chu, P. K. Angew. Chem. Int. Ed. 2015, 54, 11526. doi: 10.1002/anie.201506154
109. [109]
  Cheng, L.; Liu, J.; Gu, X.; Gong, H.; Shi, X.; Liu, T.; Wang, C.; Wang, X.; Liu, G.; Xing, H.; et al. Adv. Mater. 2014, 26, 1886. doi: 10.1002/adma.201304497
110. [110]
  Yong, Y.; Cheng, X.; Bao, T.; Zu, M.; Yan, L.; Yin, W.; Ge, C.; Wang, D.; Gu, Z.; Zhao, Y. ACS Nano 2015, 9, 12451. doi: 10.1021/acsnano.5b05825
111. [111]
  Li, J.; Jiang, F.; Yang, B.; Song, X. R.; Liu, Y.; Yang, H. H.; Cao, D. R.; Shi, W. R.; Chen, G. N. Sci. Rep. 2013, 3, 1998. doi: 10.1038/srep01998
112. [112]
  Pham, V. T.; Truong, V. K.; Quinn, M. D.; Notley, S. M.; Guo, Y.; Baulin, V. A.; Al Kobaisi, M.; Crawford, R. J.; Ivanova, E. P. ACS Nano 2015, 9, 8458. doi: 10.1021/acsnano.5b03368
113. [113]
  Xiong, Z.; Zhang, X.; Zhang, S.; Lei, L.; Ma, W.; Li, D.; Wang, W.; Zhao, Q.; Xing, B. Ecotox. Environ. Safe. 2018, 161, 507. doi: 10.1016/j.ecoenv.2018.06.008
114. [114]
  Hui, L.; Auletta, J. T.; Huang, Z.; Chen, X.; Xia, F.; Yang, S.; Liu, H.; Yang, L. ACS Appl. Mater. Interfaces 2015, 7, 10511. doi: 10.1021/acsami.5b02008
115. [115]
  Yin, W.; Yu, J.; Lv, F.; Yan, L.; Zheng, L. R.; Gu, Z.; Zhao, Y. ACS Nano 2016, 10, 11000. doi: 10.1021/acsnano.6b05810
116. [116]
  Bang, G. S.; Cho, S.; Son, N.; Shim, G. W.; Cho, B. K.; Choi, S. Y. ACS Appl. Mater. Interfaces 2016, 8, 1943. doi: 10.1021/acsami.5b10136

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沈阳化工大学材料科学与工程学院沈阳 110142

二维材料“遇见”生物大分子：机遇与挑战

通讯作者: 杜春保, duchunbao218@126.com; 程渊, chengy@ihpc.a-star.edu.sg

English

2D Materials Meet Biomacromolecules: Opportunities and Challenges

Corresponding author: Emails: duchunbao218@126.com (D.C.); Emails: chengy@ihpc.a-star.edu.sg (C.Y.)

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

二维材料“遇见”生物大分子：机遇与挑战

通讯作者: 杜春保, duchunbao218@126.com; 程渊, chengy@ihpc.a-star.edu.sg

English

2D Materials Meet Biomacromolecules: Opportunities and Challenges

Corresponding author: Emails: duchunbao218@126.com (D.C.); Emails: chengy@ihpc.a-star.edu.sg (C.Y.)

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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