A new series of emodin derivatives with bone affinity

Hong Chen Ying Wang Ling Leng Mao Sheng Cheng Peng Fei Yu Jing Ze Zhang

引用本文: Hong Chen,  Ying Wang,  Ling Leng,  Mao Sheng Cheng,  Peng Fei Yu,  Jing Ze Zhang. A new series of emodin derivatives with bone affinity[J]. Chinese Chemical Letters, 2007, 18(2): 141-144. doi: 10.1016/j.cclet.2006.12.021 shu
Citation:  Hong Chen,  Ying Wang,  Ling Leng,  Mao Sheng Cheng,  Peng Fei Yu,  Jing Ze Zhang. A new series of emodin derivatives with bone affinity[J]. Chinese Chemical Letters, 2007, 18(2): 141-144. doi: 10.1016/j.cclet.2006.12.021 shu

A new series of emodin derivatives with bone affinity

  • 基金项目:

    This work was supported by the National Natural Science Foundation of China (no. 30371682).

摘要: A new series of bone affinity compounds were synthesized by linking emodin with 5-fluorouracil derivatives. Their bone affinities were established by hydroxyapative (HA) affinity experiment in vitro, and their cytostatic effects were shown by the MTT assay.

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  • 收稿日期:  2006-09-01
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