引用本文:
Guang Ya XIANG, Heiner ECKSTEIN. Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment[J]. Chinese Chemical Letters,
2004, 15(7): 768-770.
Citation: Guang Ya XIANG, Heiner ECKSTEIN. Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment[J]. Chinese Chemical Letters, 2004, 15(7): 768-770.
Citation: Guang Ya XIANG, Heiner ECKSTEIN. Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment[J]. Chinese Chemical Letters, 2004, 15(7): 768-770.
Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment
摘要:
The enzymatic synthesis of a tetrapeptide Phac-Met-Gly-Trp-Met-OEt is reported. It was synthesized by coupling Phac-Met-OEt with Gly-OMe·HCl, Trp-OMe and Met-OEt successively, catalyzed by α-chymotrypsin, papain and α-chymotrypsin respectively. The results of FAB-MS showed that the products had the correct molecular mass.
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关键词:
- CCK-8
- / enzymatic method
- / α-chymotrypsin
- / papain
English
Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment
Abstract:
The enzymatic synthesis of a tetrapeptide Phac-Met-Gly-Trp-Met-OEt is reported. It was synthesized by coupling Phac-Met-OEt with Gly-OMe·HCl, Trp-OMe and Met-OEt successively, catalyzed by α-chymotrypsin, papain and α-chymotrypsin respectively. The results of FAB-MS showed that the products had the correct molecular mass.
-
Key words:
- CCK-8
- / enzymatic method
- / α-chymotrypsin
- / papain
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