N-(2-(2-Methoxyphenylthio)benzyl)-2-aryloxyethylamines: Synthesis and evaluation for dual 5-HT_1A/SSRI activities

• Xue Dan Wu ^a, ,
• Dong Zhi Liu ^a, ,
• Ai Jun Li ^a,b, ,
• Xue Qin Zhou ^a,

• a School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China;

• b College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China

• Received Date: 05 November 2007
  
• Fund Project:

  This work was supported by the National Natural Science Foundation of China (No. 20576094). We also thank Prof. Chen Naihong for determining affinity at the 5-HTT and 5-HT1A receptor.