<sup>31</sup>p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

引用本文: Guo TANG, Gui Ji ZHOU, Feng NI, Li Ming HU, Yu Fen ZHAO. ³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes[J]. Chinese Chemical Letters, 2005, 16(3): 385-388. shu

Citation: Guo TANG, Gui Ji ZHOU, Feng NI, Li Ming HU, Yu Fen ZHAO. ³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes[J]. Chinese Chemical Letters, 2005, 16(3): 385-388. shu

³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

1.
The Key Laboratory for Chemical Biology of Fujian Province, Department of Chemistry, Xiamen University, Xiamen 361005;
2.
The Key laboratory for Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084
基金项目:
The authors would like to thank the financial supports from the Fujian Foundation of Science and Technology(2001F008) and Fujian key Foundation of Science and Technology(2002H011)

摘要: The intermediates of the Appel coupling reagents were studied in acetonitrile,dimethoxyethane and dioxane by ³¹P NMR,¹³C NMR spectrum and ESI-MS. In dioxane a new high coordinated phosphorous compound with ³¹p NMR shift at -39 ppm was observed. The ESI-MS showed that it could be a penta-coordinated phosphorous compound containing dioxane. The carboxyl activated intermediates were also studied in three solvents.

关键词:

Triphenylphosphine
/ hexachloroethane
/ ³¹PNMR
/ ESI-MS
/ penta-coordinated phosphorous compound.

English

³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

1.
The Key Laboratory for Chemical Biology of Fujian Province, Department of Chemistry, Xiamen University, Xiamen 361005;
2.
The Key laboratory for Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084
Received Date: 23 February 2004
Fund Project:
The authors would like to thank the financial supports from the Fujian Foundation of Science and Technology(2001F008) and Fujian key Foundation of Science and Technology(2002H011)

Abstract: The intermediates of the Appel coupling reagents were studied in acetonitrile,dimethoxyethane and dioxane by ³¹P NMR,¹³C NMR spectrum and ESI-MS. In dioxane a new high coordinated phosphorous compound with ³¹p NMR shift at -39 ppm was observed. The ESI-MS showed that it could be a penta-coordinated phosphorous compound containing dioxane. The carboxyl activated intermediates were also studied in three solvents.

Key words:

Triphenylphosphine
/ hexachloroethane
/ ³¹PNMR
/ ESI-MS
/ penta-coordinated phosphorous compound.

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1.
沈阳化工大学材料科学与工程学院沈阳 110142

³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

English

³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

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中国化学会秘书处

31p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

English

31p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

³¹p NMR and ESI-MS Studies on Some Intermediates of the Peptide Coupling Reagents Triphenyl-chlorophosphoranes

CCS Chemistry：颜徐州、鲍哲南：你的皮肤可能是一片SPMs