可穿戴式微流控芯片在体液检测和药物递送中的研究进展

引用本文: 范一强, 高峰, 王玫, 庄俭, 唐刚, 张亚军. 可穿戴式微流控芯片在体液检测和药物递送中的研究进展[J]. 分析化学, 2017, 45(3): 455-463. doi: 10.11895/j.issn.0253-3820.160623 shu

Citation: FAN Yi-Qiang, GAO Feng, WANG Mei, ZHUANG Jian, TANG Gang, ZHANG Ya-Jun. Recent Development of Wearable Microfluidics Applied in Body Fluid Testing and Drug Delivery[J]. Chinese Journal of Analytical Chemistry, 2017, 45(3): 455-463. doi: 10.11895/j.issn.0253-3820.160623 shu

可穿戴式微流控芯片在体液检测和药物递送中的研究进展

北京化工大学机电工程学院, 北京 100029

摘要: 可穿戴式微流控芯片在医疗、体育、军事等领域具有广泛的应用潜力，利用可穿戴式微流控芯片对人体体液进行实时监测，可以通过芯片与皮肤的接触，方便地对汗液、泪液、唾液等体液进行采集，并分析和传输数据，可以实时获取汗液pH值以及血糖、乳酸盐、钠/钾离子、钙离子、重金属等的含量的信息，这些体液信息对于个体生命体征的实时监测和疾病诊断有着重要的指示性作用。本文介绍了近年来可穿戴式微流控芯片在体液检测和药物递送方面的最新研究进展，以及利用可穿戴式微流控芯片进行生命体征监测的应用案例。本文还简要介绍了利用可穿戴式微流控芯片进行精准药物递送的最新研究动向和应用进展，并对可穿戴式微流控芯片发展过程可能遇到的问题进行了分析，对未来融合发展的前景进行了展望。

关键词:

English

Recent Development of Wearable Microfluidics Applied in Body Fluid Testing and Drug Delivery

School of Mechanical and Electrical Engineering, Beijing University of Chemical Science, Beijing 100029, China
Received Date: 22 August 2016
Revised Date: 28 November 2016

Abstract: Wearable microfluidics have wide applications in medical, sports and military field. With the help of wearable microfluidics, through the direct physical contact between the chip and skin, the pH, glucose, lactate, sodium/potassium, calcium and heavy metal in the body fluid can be detected from sweat, tear and saliva without puncture for blood. And these information are of great importance for the monitoring of vital signs and disease diagnosis. This paper introduced the most recent development and applications of the wearable microfluidics in the body fluid testing and drug delivery. The up-to-date research development for the drug delivery using wearable microfluidics was also briefly introduced in this article. The forecast of the emerging trend for wearable microfluidics and discussion of potential technique barriers was also provided at the end of this article.

Key words:

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沈阳化工大学材料科学与工程学院沈阳 110142

可穿戴式微流控芯片在体液检测和药物递送中的研究进展

English

Recent Development of Wearable Microfluidics Applied in Body Fluid Testing and Drug Delivery

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

可穿戴式微流控芯片在体液检测和药物递送中的研究进展

English

Recent Development of Wearable Microfluidics Applied in Body Fluid Testing and Drug Delivery

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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